Autologous Adipose Tissue Injection in the Treatment of Alopecia: A Mini-Review

    November 2023 in “ Journal of Cosmetic Dermatology
    Sara Sadeghi, Yekta Ghane, Nima Hajizadeh, Azadeh Goodarzi
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    Studysummary This study highlights the potential of fat injections for treating alopecia, as they may promote hair regrowth, reduce inflammation, and exhibit limited adverse effects, suggesting efficacy and safety in managing the condition.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    Autologous fat grafting (AFG) is a potential treatment for various types of alopecia, including primary and secondary cicatricial alopecia, androgenic alopecia, and alopecia areata. The treatment works by inducing angiogenesis and secreting growth factors that aid hair regeneration. The adipose tissue also contains anti-inflammatory and anti-oxidative agents that prevent further damage to hair follicles. Case studies show that autologous adipose tissue (AT) injection can improve hair density, reduce inflammation, and promote hair regrowth in various alopecia cases. The combination of AFG and platelet-rich plasma (PRP) has shown significant hair regeneration and a reduction in further hair shedding. However, re-treatment may be required to maintain results. The method of AT graft processing can affect the outcome, with washing found to be the best method. Further studies with larger sample sizes are recommended to determine the efficacy and safety profile of this treatment method.
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