Association Between Metabolic Syndrome and Prevalent Skin Diseases: A Systematic Review and Meta-Analysis of Case-Control Studies

September 2023 in “ Health science reports ”

Sogand Sodagar, Yekta Ghane, Amirhossein Heidari, Nazila Heidari, Elaheh Khodadust, Seyyed Amir Yasin Ahmadi, Farnoosh Seirafianpour, Hamid Reza Baradaran, Azadeh Goodarzi

metabolic syndrome androgenic alopecia lichen planus hidradenitis suppurativa vitiligo psoriasis rosacea seborrheic dermatitis MetS AGA LP HS

TLDR People with certain skin conditions, especially androgenic alopecia, are more likely to have metabolic syndrome.

The systematic review and meta-analysis of 37 case-control studies found a significant association between metabolic syndrome (MetS) and several skin diseases, including androgenic alopecia (AGA), lichen planus (LP), hidradenitis suppurativa (HS), vitiligo, and psoriasis. The prevalence of MetS was significantly higher in patients with these conditions, particularly in those with AGA. However, no significant association was found between MetS and rosacea or seborrheic dermatitis. The study suggests that patients with these skin conditions should be monitored for indicators of MetS. The review also highlights the need for further studies to better understand the relationship between MetS and these skin diseases.

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