TLDR People with cutaneous Lichen Planus are more likely to have Metabolic Syndrome and related conditions like high cholesterol, diabetes, and high blood pressure.
In 2016, a case-control study involving 140 participants (70 with cutaneous Lichen Planus (LP) and 70 healthy controls) found a significant association between cutaneous LP and Metabolic Syndrome (MS). The study found that 58.6% of LP patients had MS compared to 17.1% of controls, and 81.42% of LP patients had dyslipidemia compared to 31.7% of controls. Additionally, LP patients had significantly higher mean values of waist circumference, Body Mass Index (BMI), fasting blood sugar (FBS), triglycerides (TG), and both systolic and diastolic blood pressure. The study concluded that patients with cutaneous LP had a higher prevalence of MS, dyslipidemia, diabetes mellitus, and hypertension, suggesting the need for cardiovascular risk factor investigation and lifestyle modification in these patients. No significant association was found between gender, the concomitant involvement of oral mucosa, hair, or nail and MS.
28 citations
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July 2015 in “American Journal of Clinical Dermatology” People with Lichen Planus, especially with mucosal involvement, are more likely to have Metabolic Syndrome, which increases their risk for heart disease and diabetes.
17 citations
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January 2014 in “Journal of Clinical and Diagnostic Research” Patients with oral lichen planus or oral lichenoid reactions had worse cholesterol levels and a higher risk of obesity compared to healthy individuals.
50 citations
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January 2013 in “Indian Journal of Dermatology” Some skin conditions, like psoriasis and early-onset baldness, may indicate metabolic syndrome, and others are linked to diabetes risk and cardiovascular issues.
69 citations
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April 2010 in “British Journal of Dermatology” Balding men, especially young ones, may have higher risk of heart issues and diabetes; check cholesterol levels.
18 citations
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September 2017 in “Clinics in Dermatology” Obesity is linked to various skin disorders, which can help with early diagnosis and prevention of long-term health issues.
10 citations
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May 2025 in “Nutrition & Metabolism” Metabolic syndrome is linked to skin diseases, requiring integrated treatment and monitoring.
52 citations
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February 2018 in “Diabetology & Metabolic Syndrome” Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.
March 2020 in “International journal of contemporary medical research” Patients with metabolic syndrome often have skin problems like acanthosis nigricans and skin tags, and early treatment is important to prevent serious issues.
6 citations
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December 2023 in “Journal of Clinical Medicine” Abnormal growth factor metabolism may link psoriasis and metabolic syndrome, and obesity can affect psoriasis treatment effectiveness.
