TLDR Fat tissue transplant may be an effective new treatment for severe, treatment-resistant hair loss from folliculitis decalvans.
In 2018, Marinella Tedesco reported on a case where autologous fat transplantation was used as a treatment for a female patient with recurrent folliculitis decalvans (FD), a scarring type of hair loss. The patient, who had suffered from FD for 25 years and was unresponsive to conventional treatments, underwent two adipose tissue transplants. Following the treatment, the patient showed no signs of new pustules, pain, or burning, and experienced hair regrowth in the affected areas, with the hair quality improving to be stronger and shinier. This case indicated that adipose tissue transplant might be an effective alternative therapy for severe and resistant FD, leading to clinical remission and reduced reliance on traditional therapy. However, the author emphasized the need for further studies with more participants and longer follow-up to confirm the treatment's efficacy.
30 citations
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July 2017 in “Stem cells and cloning” SVF-enhanced adipose transplantation shows potential as a hair loss treatment.
83 citations
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March 2015 in “International Journal of Dermatology” ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.
37 citations
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February 2015 in “Journal of the European Academy of Dermatology and Venereology” Oral isotretinoin is the most effective treatment for folliculitis decalvans.
68 citations
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February 2015 in “Journal of the European Academy of Dermatology and Venereology” Early onset and pustules indicate severe hair follicle inflammation, and while antibiotics help, the condition often worsens after treatment stops.
27 citations
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July 2013 in “Journal of dermatological treatment” Laser therapy may effectively treat persistent scalp inflammation.
39 citations
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226 citations
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27 citations
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January 2015 in “Current problems in dermatology” The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.
39 citations
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July 2000 in “British Journal of Dermatology” Identical twins both had a rare hair loss condition, suggesting it might be genetic.