research Hair Growth Promoting Effects of Human Dermal Papilla Cells in Pigs
Human dermal papilla cells can increase hair thickness and number in pigs with just one injection.
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research Effect of Deep Dermal Tissue Dislocation Injury on Skin Fibrosis in Pigs
Deep dermal tissue dislocation injury in pigs leads to thicker fibrotic tissue and increased type III collagen, affecting skin repair.
research Induction of Psoriasiform Changes in Guinea Pig Skin by Propranolol
Propranolol combined with injections caused skin changes in guinea pigs but didn't fully mimic psoriasis.
research Formulation and Evaluation of Valproic Acid Microemulsions for Enhanced Transfollicular Delivery in Guinea Pig Skin
This study focused on developing and evaluating microemulsion (ME) formulations of valproic acid (VPA) for improved transfollicular delivery in guinea pig skin. Eight stable ME formulations were created, featuring droplet sizes of 10 to 24 nm and pH levels between 4.6 and 5.2. These formulations demonstrated controlled release over 24 hours and enhanced drug delivery through both follicular and nonfollicular pathways compared to an aqueous VPA solution. The study found that formulations with higher surfactant/cosurfactant ratios improved permeation through the follicular pathway. The composition of the MEs, including oil and water content and surfactant/cosurfactant ratio, was crucial in determining the physicochemical properties and skin permeation of VPA.
research Telogen Effluvium Following Application of Selenium Disulfide in the Guinea Pig
Using selenium disulfide on guinea pigs increased hair loss.
research Determination of the Efficacy of Terbinafine Hydrochloride Nail Solution in the Topical Treatment of Dermatophytosis in a Guinea Pig Model
Terbinafine HCl nail solutions with DDAIP HCl are more effective than current treatments for nail infections.
research Topical Gene Electrotransfer to the Epidermis of Hairless Guinea Pig by Non-Invasive Multielectrode Array
The method safely and efficiently delivers genes to the skin but may not work for conditions needing high levels of gene products.
research Cross-Species Amplification of Human Microsatellite Markers in Pig-Tailed and Stump-Tailed Macaques
Some human genetic markers work for genetic studies in pig-tailed and stump-tailed macaques, which can help in their conservation.
research Formulation of Hair Tonic from Ethanol Extract of Sea Hibiscus (Hibiscus Tiliaceus L.) Leaves in Promoting Hair Growth on Guinea Pigs (Cavia Porcellus)
Sea hibiscus leaf extract at 30% concentration in a hair tonic significantly increased hair growth in guinea pigs.
research Topically Active Vitamin D3 Analogue, 1α,24-Dihydroxy-Cholecalciferol, Has an Anti-Proliferative Effect on the Epidermis of Guinea Pig Skin
A vitamin D3 compound can reduce skin cell growth.
research Efficacy of CD101, a Novel Echinocandin, in the Treatment of Dermatophytosis Using a Guinea Pig Model
CD101 is highly effective in treating dermatophytosis in guinea pigs.
research Superoxide Dismutase Loaded Niosomes Delivery to Hair Follicles: Permeation Through Synthetic Membrane and Guinea Pig Skin
Niosomes can effectively deliver Superoxide Dismutase to hair follicles, potentially helping prevent hair loss.
research Cystic Endometrial Hyperplasia and Bacterial Endometritis Associated with an Intrauterine Foreign Body in a Guinea Pig with Ovarian Cystic Disease
A guinea pig with ovarian cysts had a uterine infection and abnormal uterus lining due to a piece of hay inside it.
research Full Thickness Wound Healing in the Lanyu Pig
Full thickness wounds on Lanyu pigs' skin resulted in abnormal skin structure and function due to changes in molecular expression patterns.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Comparison of Two In Vitro Models for the Analysis of Follicular Penetration and Its Prevention by Barrier Emulsions
Pig ear skin is better than human skin for testing how well barrier creams block allergens from entering hair follicles.
research The In Vitro Use of the Hair Follicle Closure Technique to Study the Follicular and Percutaneous Permeation of Topically Applied Drugs
Hair follicles significantly affect the skin absorption of some drugs.
research Deciphering the Mesodermal Potency of Porcine Skin-Derived Progenitors by Microarray Analysis
Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
research Industrial Mass Production of Platelet Dry Powder
Pig blood can be used to mass-produce stable, low-cost platelet dry powder for medical use.
research Genetics Of Stress Hormone Concentrations In Hair Of Healthy Nursery Pigs And Their Relationship With Back Test Responses
Pig hair cortisol levels are inheritable and linked to stress responses, which could help select for more resilient pigs.
research Hydrogel from Acellular Porcine Adipose Tissue Accelerates Wound Healing by Inducing Intradermal Adipocyte Regeneration
A hydrogel made from pig fat helps wounds heal faster by regenerating skin fat cells.
research Tight Junctions Form a Barrier in Porcine Hair Follicles
Tight junctions create a barrier in pig hair follicles that controls what can enter the skin.
research Industrial-Scale Processing of Activated Platelet-Rich Plasma from Specific Pathogen-Free Pigs and Its Effect on Promoting Human Hair Follicle Dermal Papilla Cell Cultivation
Pig blood plasma can be used to promote human hair growth and is a good alternative to the commonly used serum additive.
research Determination of Permeation Pathway of Gentamicin into Pig's Ear Skin
Gentamicin penetrates pig skin better through open hair follicles than blocked ones.
research Hair Growth Promoting Potential of Phospholipids Purified from Porcine Lung Tissues
Phospholipids from pig lungs can significantly promote hair growth.
research Antianaphylactic Activity of Alcoholic Extract of Eclipta Alba
Alcoholic extract of Eclipta alba may help treat allergies and is safe at high doses.
research A Novel Microparticle-Based Formulation for Topical Delivery of FOL-005, a Small Peptide
The new skin cream with FOL-005 safely promotes hair growth and is stable and user-friendly.
research Secreted Subtilisin Sub3 from Microsporum Canis Is Required for Adherence to but Not for Invasion of the Epidermis
Sub3 is essential for fungus adherence but not for skin invasion.
research Preparation and Characterization of Dutasteride-Loaded Nanostructured Lipid Carriers Coated with Stearic Acid-Chitosan Oligomer for Topical Delivery
The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.
research LGR5 Is a Conserved Marker of Hair Follicle Stem Cells in Multiple Species and Is Present Early and Throughout Follicle Morphogenesis
LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.