TLDR Pig blood can be used to mass-produce stable, low-cost platelet dry powder for medical use.
The study developed a method for industrial mass production of platelet dry powder from pig blood, achieving a platelet concentration 15 times higher than whole blood using calcium chloride as an activator. Different calcium chloride concentrations affected growth factor levels, with 20% yielding the highest TGF-β1 and 10% the highest PDGF-BB. The powder maintained over 90% of its initial TGF-β1 concentration after 12 months, demonstrating long-term stability. The method is cost-effective, environmentally friendly, and offers a reliable supply for regenerative medicine and tissue engineering. The process showed high reproducibility across six batches, confirming its stability and repeatability.
60 citations,
December 2021 in “Cytokine & growth factor reviews” PRP therapy shows promise in healing and tissue repair across various medical fields but needs more research for standardization and optimization.
1 citations,
April 2018 in “Journal of Investigative Dermatology” People respond differently to hair loss treatment with PRP because of individual differences in growth factors from platelets.
348 citations,
July 2017 in “Skin appendage disorders” Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.
51 citations,
March 2019 in “Journal of cellular physiology” Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.
29 citations,
September 2020 in “International Journal of Molecular Sciences” The document concludes that freeze-dried platelet-rich plasma shows promise for medical use but requires standardization and further research.
November 2022 in “Journal of Nanobiotechnology” The developed system could effectively treat hair loss and promote hair growth.
January 2024 in “International journal of pharmaceutical sciences review and research” Indian jujube has many medicinal properties and can help treat ailments like diabetes, inflammation, and cancer.
233 citations,
February 2018 in “Polymers” Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.
