The In Vitro Use of the Hair Follicle Closure Technique to Study the Follicular and Percutaneous Permeation of Topically Applied Drugs
March 2012
in “
ATLA. Alternatives to laboratory animals
”
hair follicle closure technique hair follicles transdermal penetration caffeine diclofenac flufenamic acid ibuprofen paracetamol salicylic acid testosterone porcine skin Franz-type diffusion cells interfollicular permeation follicular permeation percutaneous permeation hair follicle closure skin penetration Voltaren Advil Tylenol aspirin pig skin Franz cells skin absorption follicle absorption skin permeation
Studysummary This study found that caffeine and flufenamic acid penetrated porcine skin more effectively through hair follicles, while the importance of the follicular pathway varied for other substances tested.
Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
Read the full study on journals.sagepub.com →