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research Influence of Application Time and Formulation Reapplication on the Delivery of Minoxidil through Hairless Mouse Skin as Measured in Franz Diffusion Cells

5 citations , January 1994 in “Skin Pharmacology and Physiology”

This study found that minoxidil forms a reservoir in the skin, allowing sustained drug delivery even after cleansing, while propylene glycol does not.

research The In Vitro Use of the Hair Follicle Closure Technique to Study the Follicular and Percutaneous Permeation of Topically Applied Drugs

12 citations , March 2012 in “ATLA. Alternatives to laboratory animals”

This study found that caffeine and flufenamic acid penetrated porcine skin more effectively through hair follicles, while the importance of the follicular pathway varied for other substances tested.

research Can mesoporous nanoparticles promote bioavailability of topical pharmaceutics?

15 citations , April 2021 in “International Journal of Pharmaceutics”

This study found that smaller mesoporous silica particles (400-600 nm) accumulated in skin furrows, suggesting their potential as carriers for enhancing the delivery of topical medications like metronidazole.

research Heat Enhanced Follicular Delivery of Isotretinoin to the Skin

8 citations , June 2019 in “Pharmaceutical research”

This study found that using short durations of heat with chemical penetration enhancers improved isotretinoin delivery to human skin, especially via the hair follicles.

research Permeation of topically applied caffeine through human skin – a comparison of in vivo and in vitro data

82 citations , May 2009 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology”

The study reported that combining the Follicular Closing Technique with the Franz diffusion cell is a valuable method for investigating follicular caffeine penetration in vitro, though kinetics differ from in vivo results.

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community My progress with dut and minox

171 upvotes 1 year ago

The user experienced hair loss and side effects from finasteride, switched to dutasteride and oral minoxidil, and saw improvements in beard and body hair but continued hair loss on the head. They plan to continue treatment and consider a hair transplant to improve results.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

76 upvotes 2 years ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community Finasteride success for androgenic alopecia by a 27M physician (NO PICTURES)

4 upvotes 10 years ago

A 27-year-old male physician improved hair density using minoxidil 5% foam and finasteride 1mg every other day, with initial sexual side effects that subsided. He recommends trying finasteride for a year but warns against dutasteride due to potential liver effects.

community 9 months on finasteride 1mg. Not sure if still receding, want thoughts

in Finasteride/Dutasteride 31 upvotes 5 months ago

The user has been on finasteride for 9 months and is unsure if it's effective, considering adding minoxidil or dutasteride. Other users suggest adding minoxidil for regrowth and discuss the pros and cons of oral versus topical treatments.

community 18-year progress pics. Fin only.

in Progress Pictures 419 upvotes 1 year ago

The user has been using finasteride for 18 years to manage hair loss and is considering starting minoxidil and possibly a hair transplant. Despite some regrowth, they are exploring additional treatments like dutasteride and oral minoxidil due to continued hair thinning.

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Hair Loss Treatments
E'franz Skin DiarySingapore · SG

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