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Glossary Gabrin Sign

phenomenon of facial skin injuries from prolonged PPE use

Gabrin Sign refers to the phenomenon where healthcare workers, particularly those on the front lines of the COVID-19 pandemic, develop pressure-related skin injuries on their faces from prolonged use of personal protective equipment (PPE) like masks and face shields. This term is named in honor of Dr. Frank Gabrin, the first U.S. emergency physician to die from COVID-19, who experienced these injuries while treating patients.

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Research

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research Androgenetic alopecia present in the majority of patients hospitalized with COVID-19: The “Gabrin sign”

119 citations , May 2020 in “Journal of The American Academy of Dermatology”

This study observed a high prevalence of androgenetic alopecia in patients hospitalized with severe COVID-19, with 79% of men and 42% of women affected, suggesting a potential link between androgen sensitivity and COVID-19 severity.

Androgenetic Alopecia in COVID-19: Comparison to Age-Matched Epidemiologic Studies and Hospital Outcomes With or Without the Gabrin Sign

research Androgenetic alopecia in COVID-19: Compared to age-matched epidemiologic studies and hospital outcomes with or without the Gabrin sign

32 citations , July 2020 in “Journal of The American Academy of Dermatology”

This study noted that among hospitalized COVID-19 patients, androgenetic alopecia was prevalent, and severe cases were associated with adverse outcomes such as respiratory failure, highlighting a possible link with androgen sensitivity.