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GlossaryGabrin Sign

phenomenon of facial skin injuries from prolonged PPE use

Gabrin Sign refers to the phenomenon where healthcare workers, particularly those on the front lines of the COVID-19 pandemic, develop pressure-related skin injuries on their faces from prolonged use of personal protective equipment (PPE) like masks and face shields. This term is named in honor of Dr. Frank Gabrin, the first U.S. emergency physician to die from COVID-19, who experienced these injuries while treating patients.

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research Androgenetic Alopecia Present in the Majority of Patients Hospitalized with COVID-19: The 'Gabrin Sign'

119 citations, May 2020 in “Journal of The American Academy of Dermatology”

Most COVID-19 patients in hospitals have androgenetic alopecia, more in men, suggesting a link between androgen sensitivity and severe COVID-19 symptoms.

Androgenetic Alopecia in COVID-19: Comparison to Age-Matched Epidemiologic Studies and Hospital Outcomes With or Without the Gabrin Sign

research Androgenetic Alopecia in COVID-19: Comparison to Age-Matched Epidemiologic Studies and Hospital Outcomes With or Without the Gabrin Sign

32 citations, July 2020 in “Journal of The American Academy of Dermatology”

AGA linked to worse COVID-19 outcomes in men.

research Reply to Comment on: The Gabrin Sign

November 2020 in “Journal of The American Academy of Dermatology”

Men with male pattern baldness may be more at risk for severe COVID-19, and anti-androgen treatments could offer protection.

research The Gabrin Sign's Potential for Identifying High-Risk Patients for COVID-19 With Androgenic Alopecia

September 2023 in “Journal of the European Academy of Dermatology and Venereology”

The Gabrin sign may help identify COVID-19 patients at high risk who also have hair loss due to male hormones.

research Comment on: The Gabrin Sign

3 citations, November 2020 in “Journal of The American Academy of Dermatology”

The document suggests that more research is needed to confirm if baldness can indicate a higher risk of severe COVID-19 in men.

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