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Nanocarriers for Optimizing the Balance Between Interfollicular Permeation and Follicular Uptake of Topically Applied Clobetasol to Minimize Adverse Effects

research Nanocarriers for Optimizing the Balance Between Interfollicular Permeation and Follicular Uptake of Topically Applied Clobetasol to Minimize Adverse Effects

69 citations, December 2015 in “Journal of Controlled Release”

Nanocapsules can improve clobetasol delivery to hair follicles, reducing side effects.

research The In Vitro Use of the Hair Follicle Closure Technique to Study the Follicular and Percutaneous Permeation of Topically Applied Drugs

12 citations, March 2012 in “ATLA. Alternatives to laboratory animals”

Hair follicles significantly affect the skin absorption of some drugs.

research Flutamide-Loaded Zein Nanocapsule Hydrogel: A Promising Dermal Delivery System for Pilosebaceous Unit Disorders

10 citations, June 2018 in “Aaps Pharmscitech”

The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.

research Tofacitinib Loaded Squalenyl Nanoparticles for Targeted Follicular Delivery in Inflammatory Skin Diseases

15 citations, November 2020 in “Pharmaceutics”

Tofacitinib nanoparticles can safely and effectively treat alopecia areata by targeting hair follicles.

research A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth

192 citations, April 2019 in “ACS nano”

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

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Community Join

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community He used Dutasteride for 20 YEARS: TL;DR Slight gains and largely stable for 20 years.

in Treatment 24 upvotes 8 months ago

John has experienced slight hair gains and stability over 20 years using Dutasteride, which is more effective than Finasteride in reducing scalp DHT and maintaining hair. Dutasteride at 0.5mg daily has a similar side effect profile to Finasteride, but at higher doses, it may increase the risk of sexual side effects.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 1 year ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community does lowering your prolactin levels regrow hair?

in Research/Science 11 upvotes 1 year ago

The potential of lowering prolactin levels to regrow hair, with a reference to Bayer's drug HMI 115 which has been indicated as having this effect. Treatments mentioned include Minoxidil and Finasteride, as well as RU58841.

community Been on dut 0.5mg daily for 12 months. I am cooked.

in Progress Pictures 10 upvotes 3 months ago

A user took finasteride for six months, then switched to dutasteride for a year, increasing the dosage over time, but hair shedding worsened. Replies suggest the issue is male pattern baldness and DHT-related.

community HMI-115: What We Know So Far. HMI-115 (also known as BAY1158061) is a new pharmaceutical drug developed by a biopharmaceutical company called Bioinvent and licensed by Bayer

in Research/Science 51 upvotes 5 months ago

HMI-115 is a new drug developed by Bioinvent and licensed by Bayer, with mixed opinions on its potential effectiveness. Some users are skeptical and prefer proven treatments like Minoxidil, finasteride, and RU58841.

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