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research The In Vitro Use of the Hair Follicle Closure Technique to Study the Follicular and Percutaneous Permeation of Topically Applied Drugs

12 citations , March 2012 in “ATLA. Alternatives to laboratory animals”

This study found that caffeine and flufenamic acid penetrated porcine skin more effectively through hair follicles, while the importance of the follicular pathway varied for other substances tested.

research Basic hair transplantation: 2007

15 citations , December 2007 in “Dermatologic Therapy”

This review discusses past hair transplantation techniques for androgenic alopecia and current research to improve results, but it reports no new clinical outcomes.

research Hair Transplantation

February 2002 in “Dermatologic Surgery”

Best hair transplant results happen when tissues are least damaged.

research Refining hair restoration technique

7 citations , March 2002 in “Aesthetic Surgery Journal”

This article describes techniques for hair restoration surgery, including using intradermal sutures for donor area closure and employing the retroauricular ellipse from a facelift as a donor site, but reports no new clinical results.

research Scratch and split: how I minimise bleeding, visible scarring and alopecia during incision and closure in the hair-bearing scalp

July 2025 in “Australasian Journal of Plastic Surgery”

In this guide, the authors describe a scalp incision technique that minimizes damage to hair follicles and results in barely noticeable scars in hair-bearing areas.

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Community Join

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community Comprehensive Microneedling Guide

292 upvotes 4 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community 2026 Official Beginner’s Guide for “I’m losing my hair, what can I do?”

in General 1005 upvotes 2 years ago

For hair loss, start with Finasteride, Minoxidil, Ketoconazole shampoo, and Microneedling. For severe cases, consider Dutasteride, oral Minoxidil, or hair transplants.

community Anybody had temples growth with 0.5 mg dutasteride.

5 upvotes 1 month ago

Dutasteride and minoxidil are used for hair loss treatment, with varying results on hairline and crown regrowth. Some users report success with a combination of topical and oral treatments, while others see limited improvement.

community Minoxidil’s mechanism of action on blood pressure as a potassium channel opening molecule

in Research 83 upvotes 7 months ago

Minoxidil works by opening potassium channels, leading to reduced blood pressure and potential side effects like reflex tachycardia. It is used for hair growth and affects blood pressure at high doses.

community Hairline stable but diffuse thinning with topical fin+min

in Finasteride 237 upvotes 7 months ago

The user experienced stable hairline but diffuse thinning after switching from oral finasteride to a topical solution of minoxidil and finasteride. They are concerned about the effectiveness of the topical treatment and are considering other options due to a recent decline in hair density.

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Learn

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learn Niacinamide

Does niacinamide support hair follicle nutrition? Niacinamide is a precursor of NAD+, a molecule cells use for energy. Whether it affects hair follicles in people has not been tested.

learn Scalp Micropigmentation

Will scalp micropigmentation damage my existing hair or follicles? Providers say SMP sits above the hair follicles and does not harm them. No study has tested this, and infection or scarring from any tattoo can affect the skin.

learn Sulforaphane

Can sulforaphane protect hair follicles from inflammation and damage? In lab and mouse studies, sulforaphane reduced markers of inflammation and oxidative stress. No human study has tested whether it protects hair follicles.

learn Fluridil

Can daily Fluridil application stop hair follicle miniaturization? The single published fluridil trial (43 men; placebo-controlled for 3 months, then all on fluridil to 9 months) reported more hairs in the growth phase, but it never measured follicle diameter and has not been replicated — so whether daily use stops miniaturization is unproven, and community users describe stabilization rather than regrowth.

learn Folic acid

How does folic acid support hair follicle health and growth at a cellular level? Folate is required for the DNA synthesis that fast-dividing hair matrix cells depend on, and severe deficiency causes anemia—but no published trial has given folic acid to people with hair loss and measured the result, so a growth effect is a mechanism, not a finding.

learn Hair Transplant

Surgery that moves hair follicles from the back of the scalp to thinning areas

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Clinics

1 / 4 results

Hair Systems
Hair Closures and Frontals UK LTDPlymouth, England · GB

Experts

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