Cross-Species Amplification of Human Microsatellite Markers in Pig-Tailed and Stump-Tailed Macaques

    June 2011 in “ Journal of Genetics
    Sapna Godavarthi, Archana Jayaraman, Ajay Gaur
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    TLDR Some human genetic markers work for genetic studies in pig-tailed and stump-tailed macaques, which can help in their conservation.
    In the 2011 study by Godavarthi, Jayaraman, and Gaur, 20 human tetranucleotide microsatellite markers were tested on 14 pig-tailed macaques and 20 stump-tailed macaques. The results showed that 11 markers were polymorphic, with pig-tailed macaques having an average of 6.6 alleles per locus and a mean observed heterozygosity (Ho) of 0.84, and stump-tailed macaques having an average of 6.4 alleles per locus with a mean Ho of 0.78. The remaining 9 markers either did not amplify or were nonpolymorphic. The study concluded that the polymorphic markers could be useful for genetic studies such as paternity testing and population genetics in these macaques, aiding in the conservation of these vulnerable species.
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