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Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Humans lost body hair relatively recently in evolution.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Cathepsin L is essential for normal hair growth and development.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Finasteride effectively blocks enzyme causing male pattern baldness.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Male pattern hair loss could hint at androgens affecting COVID-19 severity.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Different types of stem cells and their environments are key to skin repair and maintenance.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.