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Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.

PPAR-γ may be a key target for treating alopecia areata and other skin conditions.

A specific drug can help treat Lichen Planopilaris, a condition causing permanent hair loss.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.

The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.

Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Vitamin D receptor knockout mice have significant motor impairments but no cognitive deficits.

Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

MR antagonists may improve skin health and wound healing, especially in aging.

Blocking the mineralocorticoid receptor can help treat skin thinning caused by steroids.

A new treatment called SAMiRNA-AR68 increases hair count in people with hair loss, showing similar results to existing treatments but without side effects.

The study found that androgen receptors in skin cells mainly affect the focal adhesion pathway and control the caveolin-1 gene, with implications for new treatments for related diseases.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

The vitamin D receptor can work without its usual activating molecule.

TCDD disrupts skin stem cells, causing skin issues like chloracne.

Certain gene variations in the Vitamin D Receptor are linked to higher risk of female hair loss.

TDM10842, a thyroid hormone receptor activator, was found to effectively promote hair growth in mice.

Fewer GGC sequences in the androgen receptor gene improve finasteride treatment for hair loss.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

Mice without active or present vitamin D receptors maintain normal blood sugar control and islet gene expression when calcium levels are normal.

Vitamin D receptor is crucial for skin wound healing.

Prolactin and TGF-β receptor blockers might help treat hair loss.