Androgen Receptor Polymorphism-Dependent Variation in Prostate-Specific Antigen Concentrations of European Men

September 2014 in “ Cancer Epidemiology, Biomarkers & Prevention ”

Magdalena Bentmar Holgersson, Aleksander Giwercman, Anders Bjartell, Frederick C. W. Wu, Ilpo Huhtaniemi, Terence W O'Neill, Neil Pendleton, Dirk Vanderschueren, Michael E. J. Lean, Thang S. Han, Joseph D. Finn, Krzysztof Kula, Gianni Forti, Felipe F. Casanueva, György Bártfai, Margus Punab, Yvonne Lundberg Giwercman

androgen receptor AR prostate-specific antigen PSA single nucleotide polymorphism SNP CAG repeats genetic variants

Studysummary This study found that men without prostate cancer carrying the A-allele of SNP rs1204038 had a 65% higher risk of PSA levels above 3 ng/mL compared to those with the G-allele, increasing referrals for further examination.

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This meta-analysis suggests that the G allele of AR StuI polymorphism might be a potential risk factor for AGA, particularly in white populations.

Baldness And The Androgen Receptor: The AR Polyglycine Repeat Polymorphism Does Not Confer Susceptibility To Androgenetic Alopecia

research Baldness And The Androgen Receptor: The AR Polyglycine Repeat Polymorphism Does Not Confer Susceptibility To Androgenetic Alopecia

60 citations , January 2007 in “Human Genetics”

In this study, researchers found that while the SNP rs6152 is strongly associated with androgenetic alopecia, the GGN triplet repeat is not, suggesting the causative variant is likely a non-coding one.

The E211 G>A Androgen Receptor Polymorphism Is Associated With a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia

research The E211 G>A Androgen Receptor Polymorphism Is Associated With a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia

76 citations , April 2005 in “Cancer Epidemiology, Biomarkers & Prevention”

This study found that the AR-E211 A allele is associated with a lower risk of both metastatic prostate cancer and androgenetic alopecia in an Australian population.