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GlossarySingle Nucleotide Polymorphisms (SNP)

variations in a single DNA building block among individuals

Single Nucleotide Polymorphisms (SNPs) are variations at a single position in a DNA sequence among individuals. These genetic differences can influence how people develop diseases, respond to pathogens, chemicals, drugs, and other substances, making them crucial for personalized medicine and genetic research.

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research The Association of Gene Expression and Single Nucleotide Polymorphism (rs6152 SNP) in Androgen Receptor Gene with Recurrent Spontaneous Abortion in Iraqi Women

March 2021 in “Medico-Legal Update”

The androgen receptor gene doesn't affect women with recurrent spontaneous abortions, but having a mutant genotype might protect against it.

research Two Mutations at KRT74 and EDAR Synergistically Drive the Fine-Wool Production in Chinese Sheep

2 citations , May 2023 in “Journal of Advanced Research”

Two mutations in KRT74 and EDAR genes cause sheep to have finer wool.

research A Genome-Wide Association Study of Chemotherapy-Induced Alopecia in Breast Cancer Patients

32 citations , September 2013 in “Breast cancer research”

A specific gene variant is linked to a higher risk of hair loss from chemotherapy in breast cancer patients.

research Enhanced Ectodysplasin-A Receptor Signaling Alters Multiple Fiber Characteristics to Produce the East Asian Hair Form

98 citations , June 2008 in “Human mutation”

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

A Replication Study Confirmed the EDAR Gene to Be a Major Contributor to Population Differentiation Regarding Head Hair Thickness in Asia

research A Replication Study Confirmed the EDAR Gene to Be a Major Contributor to Population Differentiation Regarding Head Hair Thickness in Asia

89 citations , August 2008 in “Human genetics”

The EDAR gene greatly affects hair thickness in Asian populations.

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community Switched from finasteride to dutasteride - 2 month update

in Finasteride/Dutasteride 6 upvotes 2 years ago

The user switched from finasteride to dutasteride for hair loss treatment, but experienced increased libido, itchy scalp, and accelerated hair loss. Another user suggested that genetic variations might cause dutasteride to be less effective and recommended checking for specific genetic markers.

community M44 Hairloss Trichotest and Finasteride

in Finasteride/Dutasteride 6 upvotes 2 years ago

User received Trichotest results not recommending Finasteride. They are on Oral Minoxidil 2.50 and considering adding Finasteride.

community Tricho test suggested topical spironolactone. Any experience with it?

in Treatment 7 upvotes 2 years ago

The conversation is about a person experiencing hair loss, using topical minoxidil for 8 years, now at Norwood scale 3, and considering topical spironolactone and oral minoxidil after a tricho test recommendation. They are seeking others' experiences with topical spironolactone.

community Using 23andme to insight minoxidil response / SULT1A1 activity

in Minoxidil 10 upvotes 4 years ago

The conversation discusses using 23andme to determine if someone might respond well to minoxidil for hair loss treatment, and mentions the user's personal experience with micro-needling and minoxidil.

community Thin spots over time even with Finasteride

in Progress Pictures 132 upvotes 1 year ago

A user shared their experience with Finasteride for hair loss, noting improvement but still some thinning. They plan to get a hair transplant to address remaining thin spots and strengthen their hairline.

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