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GlossarySingle Nucleotide Polymorphisms (SNP)

variations in a single DNA building block among individuals

Single Nucleotide Polymorphisms (SNPs) are variations at a single position in a DNA sequence among individuals. These genetic differences can influence how people develop diseases, respond to pathogens, chemicals, drugs, and other substances, making them crucial for personalized medicine and genetic research.

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research Characterization of X-Linked SNP Genotypic Variation in Globally Distributed Human Populations

31 citations, January 2010 in “GenomeBiology.com (London. Print)”

The research concluded that selection significantly shaped the genetic variation of the X chromosome, with certain regions affected by past selective events.

Candidate SNP Markers of Reproductive Potential Predicted by Significant Change in Affinity of TATA-Binding Protein for Human Gene Promoters

research Candidate SNP Markers of Reproductive Potential Predicted by Significant Change in Affinity of TATA-Binding Protein for Human Gene Promoters

16 citations, February 2018 in “BMC Genomics”

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

research Association of HSPA1B SNP rs6457452 With Alopecia Areata in the Korean Population

12 citations, December 2013 in “Immunological Investigations”

The SNP rs6457452 is linked to a higher risk of alopecia areata in Koreans.

Androgenetic Alopecia and Polymorphism of the Androgen Receptor Gene (SNP rs6152) in Patients with Benign Prostate Hyperplasia or Prostate Cancer

research Androgenetic Alopecia and Polymorphism of the Androgen Receptor Gene (SNP rs6152) in Patients with Benign Prostate Hyperplasia or Prostate Cancer

11 citations, January 2015 in “Journal of The European Academy of Dermatology and Venereology”

Hair loss gene linked to prostate issues.

The Use of High-Density SNP Array to Map Homozygosity in Consanguineous Families to Efficiently Identify Candidate Genes: Application to Woodhouse-Sakati Syndrome

research The Use of High-Density SNP Array to Map Homozygosity in Consanguineous Families to Efficiently Identify Candidate Genes: Application to Woodhouse-Sakati Syndrome

7 citations, January 2015 in “Case reports in genetics”

Using SNP array testing helped quickly find the gene causing Woodhouse-Sakati syndrome in two related individuals.

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community Using 23andme to insight minoxidil response / SULT1A1 activity

in Minoxidil 10 upvotes 3 years ago

The conversation discusses using 23andme to determine if someone might respond well to minoxidil for hair loss treatment, and mentions the user's personal experience with micro-needling and minoxidil.

community 2 years Fin + Minoxidil Regrowth

in Finasteride/Dutasteride 113 upvotes 5 months ago

A user shared their two-year progress using 2.5mg finasteride daily and minoxidil twice daily, recently adding topical dutasteride. Another user questioned the high finasteride dosage, noting no benefits over 1mg.

community Thin spots over time even with Finasteride

in Progress Pictures 132 upvotes 8 months ago

A user shared their experience with Finasteride for hair loss, noting improvement but still some thinning. They plan to get a hair transplant to address remaining thin spots and strengthen their hairline.

community M44 Hairloss Trichotest and Finasteride

in Finasteride/Dutasteride 6 upvotes 1 year ago

User received Trichotest results not recommending Finasteride. They are on Oral Minoxidil 2.50 and considering adding Finasteride.

community Fagron TrichoTest says Finasteride won't help

in Treatment 11 upvotes 5 months ago

The user received a Fagron TrichoTest indicating that Finasteride, Dutasteride, and Minoxidil are not effective for them, recommending Latanoprost, Spironolactone, IGrantine-F1 TM, and Trichoxidil instead. Other users expressed skepticism about the test's validity and suggested sticking with proven treatments like Finasteride and Dutasteride.

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