A Novel Actor in Skin Biology: The Mineralocorticoid Receptor
October 2015
in “
Experimental dermatology
”
mineralocorticoid receptor MR hair follicle morphogenesis epidermal homeostasis MR knockout epidermal thickness differentiation marker expression glucocorticoid receptor GR skin atrophy alopecia MR antagonists spironolactone eplerenone topical MR blockers glucocorticoid-induced skin damage dermato-endocrinology hair follicle development skin balance skin thinning hair loss MR blockers Aldactone Inspra skin damage from steroids skin hormone study
Studysummary This study found that topical MR blockers alongside glucocorticoids may limit glucocorticoid-induced skin atrophy, suggesting MR's significant role in skin-related endocrinology.
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