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    5 / 1000+ results

      research A novel actor in skin biology: the mineralocorticoid receptor

      7 citations , October 2015 in “Experimental dermatology”
      This study found that topical MR blockers alongside glucocorticoids may limit glucocorticoid-induced skin atrophy, suggesting MR's significant role in skin-related endocrinology.

      research Ectoin attenuates cortisone‐induced skin issues by suppression GR signaling and the UVB‐induced overexpression of 11β‐HSD1

      September 2024 in “Journal of Cosmetic Dermatology”
      In this study, researchers found that Ectoin, derived from halophilic bacteria, can mitigate stress-related skin damage by reducing cortisone's inhibitory effects on essential skin proteins and decreasing UVB-induced glucocorticoid activity, highlighting its potential as a preventative agent for stress-induced skin issues.

      research Pathobiology of chemotherapy-induced hair loss

      218 citations , January 2013 in “The Lancet Oncology”
      This review discusses the pathobiology of chemotherapy-induced alopecia and highlights challenges in managing it, reporting no new clinical results and emphasizing the need for well-designed preclinical models to develop effective treatments.

      research An overview of animal models induced by glucocorticoids

      September 2023 in “Physiology and Pharmacology”
      This review provides an overview of various animal models used to study glucocorticoid-induced humanlike disorders, highlighting their utility in understanding side effects across multiple body systems, such as hypertension, osteoporosis, and depression-like behavior.

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      community DHT is NOT very important for adults, is it?

       124 upvotes 5 months ago
      A user experienced negative side effects, including low libido and lack of motivation, after using finasteride for hair loss and felt better after stopping it. Others shared similar experiences with finasteride and dutasteride, while some reported no side effects, showing varied individual responses.

      community Got prescribed clobetasol propionate 0.05%

       5 upvotes 2 weeks ago
      The user is experiencing diffuse thinning and receded hairline, using dutasteride, minoxidil, and ketoconazole without regrowth, and was prescribed clobetasol propionate 0.05% with salicylic acid for possible inflammation. Other users caution against using the strong steroid without a serious condition, sharing experiences of adverse effects and alternative treatments for scalp issues.

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