16 citations,
March 2021 in “Frontiers in cell and developmental biology” A new method using Y-27632 improves the growth and quality of human hair follicle stem cells for tissue engineering and therapy.
128 citations,
August 2020 in “Cell stem cell” Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.
16 citations,
May 2015 in “Tissue Engineering Part C-methods” A two-step method was created in 2015 to make more cells that help with hair growth, but they need to be combined with other cells for 4 days to actually form new hair.
12 citations,
May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Laminin 332 is essential for normal skin cell behavior and structure.
3 citations,
January 2023 in “Science advances” The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.
126 citations,
August 2018 in “Molecular Systems Biology” Fibroblast state switching is crucial for skin healing and development.
79 citations,
January 2018 in “Wiley Interdisciplinary Reviews-Developmental Biology” Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
November 2023 in “Materials Today Bio” Light therapy might help treat hereditary hair loss by improving hair follicle growth in lab cultures.
21 citations,
May 2022 in “Frontiers in Cell and Developmental Biology” Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.
31 citations,
September 2013 in “Stem Cells” Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.
August 2023 in “Research Square (Research Square)” Two microRNAs affect hair follicle development in sheep by targeting specific genes.
4 citations,
September 2020 in “BioMed Research International” Timosaponin BII, a plant extract, was found to promote hair growth in mice, similarly to minoxidil.
13 citations,
April 2019 in “iScience” EGFR helps control how hair grows and forms without needing p53 protein.
November 2022 in “Journal of Nanobiotechnology” The developed system could effectively treat hair loss and promote hair growth.
949 citations,
January 2001 in “Cell” Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.
8 citations,
August 2014 in “Biochemical and Biophysical Research Communications” ODC overexpression in hair cells increases tumor growth by reducing Notch signaling.
65 citations,
May 2017 in “Advances in wound care” Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.
75 citations,
October 2016 in “Genes & Development” Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
July 2024 in “Journal of Nanobiotechnology” Mouse cell exosomes help hair regrowth and wound healing by activating a specific signaling pathway.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
60 citations,
April 2012 in “Physiology” The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
44 citations,
July 2016 in “Stem Cells Translational Medicine” Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.
13 citations,
September 2019 in “EBioMedicine” sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.
65 citations,
February 2017 in “Pflügers Archiv - European Journal of Physiology” Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.
26 citations,
May 2016 in “Journal of biological chemistry/The Journal of biological chemistry” sPLA2-IIE is crucial for normal hair follicle structure and skin health.
10 citations,
January 1985 in “Elsevier eBooks” Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.
37 citations,
April 2017 in “npj Regenerative Medicine” PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.
10 citations,
June 2016 in “Cell Transplantation” Sebaceous glands can help harvest hair follicle stem cells to regenerate skin and hair.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.