May 2023 in “Metabolites” In this study, adding α-lactalbumin to myo-inositol treatment improved ovulation rates, menstrual cycle duration, and hyperandrogenism in women with PCOS more effectively than myo-inositol alone, suggesting potential benefits for those resistant to inositol treatment.
2 citations
,
November 2017 in “Gynecological Endocrinology” This study found that serum myo-inositol oxygenase levels do not differ between women with polycystic ovary syndrome and healthy controls, suggesting that MI deficiency in PCOS is not due to MIOX levels.
February 2025 in “Pharmaceuticals” This study found that supplementing myo-inositol with microlipodispersed magnesium significantly improved acne and hirsutism in women with PCOS by reducing BMI, testosterone, and DHEAS levels, also enhancing quality of life without side effects, over 6 months.
258 citations
,
July 2016 in “Reproductive Biology and Endocrinology” This abstract reviews the characteristics and health risks associated with polycystic ovary syndrome and does not report new findings, highlighting the syndrome's multifactorial nature.
64 citations
,
November 2012 in “EMBO reports” This review discusses the role of lamins in development, tissue maintenance, and stress response, and does not report new experimental findings.
54 citations
,
August 2017 in “Gynecological Endocrinology” This review discusses treatments for polycystic ovary syndrome, including lifestyle changes, oral contraceptives, and various medications, and reports no new clinical findings; the authors highlight the potential of statins and inositol for managing symptoms.
3 citations
,
March 2020 in “Dermatology Research and Practice” In this study, 33 overweight women with normal hormone levels but showing PCOS symptoms experienced substantial reductions in acne lesions and improvements in hirsutism and menstrual irregularities after 8 weeks of Tracnil™ treatment, with minimal adverse reactions reported.
1 citations
,
June 2019 in “Innovare journal of medical sciences” This review examines the use of natural remedies, including various herbs, for treating polycystic ovary syndrome, but reports no new clinical results.
November 2025 in “Essential Chem” In this study, Eclipta alba extract showed potential for hair regrowth by increasing the proliferative activity of human dermal papilla cells by 45% in vitro, with evidence suggesting activation of the Wnt signaling pathway.
August 2024 in “Indian Journal Of Clinical Practice” A balanced diet and healthy lifestyle help manage PCOS symptoms.
February 2025 in “Journal of Neonatal Surgery” This study explores the role of antidiabetic medications, particularly metformin, GLP-1 receptor agonists, and DPP-4 inhibitors, in managing PCOS, highlighting their combination with hormonal therapies and lifestyle interventions for a comprehensive treatment approach.
10 citations
,
January 2014 in “Endocrinology & metabolic syndrome” This review summarizes the current knowledge on polycystic ovary syndrome, including its features, diagnosis, and treatment, and highlights the need for further research to fill existing knowledge gaps.
4 citations
,
December 2023 in “PubMed” This review discusses dietary interventions as a modifiable factor in managing hidradenitis suppurativa and reports no new clinical results, emphasizing the need for informed lifestyle choices.
November 2017 in “Elsevier eBooks” This article reviews the complications and health risks associated with polycystic ovary syndrome and reports no new clinical findings.
883 citations
,
August 2016 in “Nature Reviews Disease Primers” This review discusses the current understanding of polycystic ovary syndrome, focusing on its epidemiology, pathophysiology, diagnosis, management, and future research directions, but reports no new clinical results.
58 citations
,
November 2020 in “International Journal of Molecular Sciences” This review discusses the relationship between SHBG, NAFLD, and PCOS and reports no new clinical results; the authors highlight low hepatic SHBG production as potentially significant in PCOS pathogenesis.
45 citations
,
February 2019 in “Journal of Affective Disorders” This study found that 12 weeks of melatonin supplementation improved mental health and metabolic parameters in women with polycystic ovary syndrome compared to a placebo.
36 citations
,
October 2021 in “Frontiers in Endocrinology” This study highlights the importance of understanding the roles of hyperandrogenemia and insulin resistance in the development and progression of PCOS, emphasizing further research to clarify their mutual influence.
30 citations
,
September 2017 in “Clinics in Dermatology” This article reviews the clinical and histological features of acanthosis nigricans and its associations with insulin resistance and other conditions, but highlights the need for more research on its classification, severity assessment, and treatment options.
21 citations
,
September 2017 in “Journal of Obstetrics and Gynaecology Research” This meta-analysis found that chromium supplementation was associated with decreased insulin resistance but increased testosterone levels in women with PCOS, with no significant benefits for other metabolic or hormonal indexes.
12 citations
,
January 2010 in “Pediatric Health” This review discusses treatment strategies for PCOS, focusing on using insulin-sensitizing medications alongside weight reduction and exercise to improve hyperinsulinemia and hyperandrogenism, and reports no new results.
11 citations
,
April 2019 in “International Journal of Molecular Sciences” This study found that genetic polymorphisms of OCT1 influence the effectiveness of metformin treatment in improving insulin sensitivity among PCOS patients, suggesting a role for personalized treatment strategies.
10 citations
,
November 2024 in “Cureus” This systematic review identified several factors contributing to increased cardiovascular risk in women with polycystic ovary syndrome, including insulin resistance, obesity, inflammation markers, and microbiota alterations linked to elevated trimethylamine-N-oxide levels.
9 citations
,
December 2024 in “Clinical and Experimental Obstetrics & Gynecology” This review examines the impact of polycystic ovary syndrome on reproductive health, its pathophysiology, clinical manifestations, and emerging therapies, and reports no new findings; the authors emphasize the need for individualized treatment strategies.
7 citations
,
January 2024 in “Medicinska istrazivanja” This review outlines the complexities and varied manifestations of polycystic ovary syndrome, highlighting challenges in diagnosis and management but reports no new clinical findings.
5 citations
,
October 2021 in “Meditsinskiy sovet = Medical Council” This review discusses diagnostic criteria, phenotypes, and therapies for polycystic ovarian syndrome, emphasizing an individualized treatment approach based on the multifactorial nature of the disease; it reports no clinical results.
5 citations
,
October 2021 in “Journal of Ovarian Research” This review indicates promising potential for cinnamon supplementation to improve metabolic outcomes in PCOS, but more clinical trials with higher doses and longer durations are needed to confirm these effects.
5 citations
,
May 2017 in “Current Opinion in Pediatrics” This review found that hormonal therapies, including FDA-approved combined oral contraceptive pills and spironolactone, are effective and well-tolerated treatments for acne vulgaris in adolescents with or without endocrine disorders, providing alternative options to antibiotics.
4 citations
,
January 2022 in “Open Health” This article discusses the challenges in treating PCOS, highlights the role of lifestyle interventions, and notes the lack of effective treatment beyond symptomatic management for this common reproductive health issue.
4 citations
,
July 2019 in “Children (Basel)” This review discusses recent findings on pathogenic mechanisms, diagnostic criteria, and treatment options for PCOS but reports no new clinical results.