Endocrine Disorders and Hormonal Therapy for Adolescent Acne

    May 2017 in “ Current Opinion in Pediatrics ”
    Henry Nguyen, Megha M. Tollefson
    Studysummary This review found that hormonal therapies, including FDA-approved combined oral contraceptive pills and spironolactone, are effective and well-tolerated treatments for acne vulgaris in adolescents with or without endocrine disorders, providing alternative options to antibiotics.
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    Research cited in this study 15

    1. Cutaneous Findings and Systemic Associations in Women With Polycystic Ovary Syndrome JAMA Dermatology · 2015
    2. Comparison of Two Contraceptive Pills Containing Drospirenone and 20 μg or 30 μg Ethinyl Estradiol for Polycystic Ovary Syndrome International Journal of Gynecology & Obstetrics · 2015
    3. Evidence-Based Approach to Cutaneous Hyperandrogenism in Women Journal of The American Academy of Dermatology · 2015
    4. Linking Diet to Acne Metabolomics, Inflammation, and Comedogenesis: An Update Clinical, Cosmetic and Investigational Dermatology · 2015
    5. Mixed Form of Hirsutism in Adolescent Females and Laser Therapy Iranian Red Crescent medical journal · 2014
    6. Acne as a Chronic Systemic Disease Clinics in Dermatology · 2013
    7. Ovarian SAHA Syndrome Is Associated With a More Insulin-Resistant Profile and Represents an Independent Risk Factor for Glucose Abnormalities in Women With Polycystic Ovary Syndrome: A Prospective Controlled Study Journal of The American Academy of Dermatology · 2013
    8. Hepatotoxicity with Low- and Ultralow-Dose Flutamide: A Surveillance Study on 203 Hyperandrogenic Young Females Fertility and Sterility · 2012
    9. Congenital Adrenal Hyperplasia: Comprehensive Overview and Clinical Management Journal of Pediatric and Adolescent Gynecology · 2011
    10. Acne-Associated Syndromes: Models for Better Understanding of Acne Pathogenesis Journal of The European Academy of Dermatology and Venereology · 2010
    11. Nonclassic Congenital Adrenal Hyperplasia International Journal of Pediatric Endocrinology · 2010
    12. Pharmacology of Different Progestogens: The Special Case of Drospirenone Climacteric · 2005
    13. Clinical Profiles, Occurrence, and Management of Adolescent Patients with HAIR-AN Syndrome ˜The œscientific world journal/TheScientificWorldjournal · 2004
    14. Update and Future of Hormonal Therapy in Acne Dermatology · 2003
    15. Successful Treatment of Hirsutism in HAIR-AN Syndrome Using Flutamide, Spironolactone, and Birth Control Therapy Archives of dermatology · 1997