Exploring Melatonin’s Multifaceted Role in Polycystic Ovary Syndrome Management: A Comprehensive Review

November 2023 in “ Curēus ”

Ankur Patel, Deepika Dewani, Arpita Jaiswal, Pallavi Yadav, Linda A. Reddy

melatonin Polycystic Ovary Syndrome PCOS insulin sensitivity sex hormones gonadotropins hormonal imbalances antioxidant anti-inflammatory oxidative stress

TLDR Melatonin may help manage PCOS by improving insulin sensitivity, hormone balance, and mood.

This review examines melatonin's multifaceted role in managing Polycystic Ovary Syndrome (PCOS), highlighting its potential to enhance insulin sensitivity, regulate sex hormones, and influence gonadotropins, thereby addressing hormonal imbalances. Melatonin's antioxidant and anti-inflammatory properties help mitigate oxidative stress, while its benefits on sleep quality and mood can improve psychological well-being and daily functioning in PCOS patients. The review suggests melatonin as a promising complementary therapy to existing PCOS treatments, though further research is needed to fully understand its benefits.

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Exploring Melatonin’s Multifaceted Role in Polycystic Ovary Syndrome Management: A Comprehensive Review

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