research Alopecia in IL-10-Deficient Mouse Pups Is c-Kit-Dependent and Can Be Triggered by Iron Deficiency
Hair loss in certain young mice is linked to a specific gene and can be caused by lack of iron.
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300-330 / 1000+ results research Overexpression of Spermidine/Spermine N1-Acetyltransferase Under the Control of Mouse Metallothionein I Promoter in Transgenic Mice: Evidence for a Striking Post-Transcriptional Regulation of Transgene Expression by a Polyamine Analogue
Overexpressing SSAT in mice makes them highly sensitive to polyamine analogues, causing liver damage and high mortality.
research Live Imaging of Smad2/3 Signaling in Mouse Skin Wound Healing
Smad2/3-dependent TGF-β signaling increases during wound healing.
research Molecular and Spatial Landmarks of Early Mouse Skin Development
The research maps the complex development of early mouse skin, identifying diverse cell types and their roles in forming skin layers and structures.
research Lgr6+ Stem Cells and Their Progeny in Mouse Epidermis Under Regimens of Exogenous Skin Carcinogenesis, and Their Absence in Ensuing Skin Tumors
UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.
research Standard DNA Methylation Analysis in Mouse Epidermis: Bisulfite Sequencing, Methylation-Specific PCR, and 5-Methyl-Cytosine Immunological Detection
These methods help understand DNA changes in mouse skin.
research Itpr3 Is Responsible for the Mouse Tufted (tf) Locus
The Itpr3 gene causes a specific hair pattern in mice.
research Thiosulfate Promotes Hair Growth in Mouse Model
Thiosulfate may help hair grow faster in mice and works well with a common hair growth treatment.
research Dermal Lymphatic Dilation in a Mouse Model of Alopecia Areata
Mice with alopecia areata had wider lymphatic vessels in their skin.
research Differential Expression of a Gene Homologous to a G-Alpha Protein Gene in Neonatal Mouse Skin During Development of Hair Follicles
The G(S) alpha subunit gene may help start hair follicle growth in newborn mice.
research Identification of Bulge Stem Cells in Mouse and Human Hair Follicles
Scientists found markers called CD34 and CD200 that help identify stem cells in mouse and human hair follicles.
research Expression of Apoptosis-Related Genes in the Mouse Skin During the First Postnatal Catagen Stage, Focused on Localization of Bnip3L and Caspase-12
The research found changes in gene expression related to cell death in mouse skin that help understand hair follicle development and skin health.
research Hair Growth Effects of Laminaria Japonica Extract and Growth Factor Mixture on a C57BL/6 Mouse Model
Laminaria japonica extract with IGF-1 improved mouse hair growth and could be a potential alopecia treatment.
research Detection of Bim and Puma in Mouse Hair Follicles Using Immunofluorescence and TUNEL Assay Double Staining
Bim and Puma proteins are found in developing mouse hair follicles and are involved in more than just cell death.
research Skin and Adnexa of the Laboratory Mouse
research Blue Laser Irradiation Decreases ATP Levels in Mouse Skin and Increases Production of Superoxide Anion and Hypochlorous Acid in Mouse Fibroblasts
Blue laser light reduces energy in mouse skin cells and creates harmful oxygen compounds, possibly harming the cells.
research Hair Growth Is Promoted in Mouse Dorsal Skin by a Mixture of Platycladus Orientalis Leaf Extract and Alpha-Terpineol by Increasing Growth Factors and Wnt3/β-Catenin
A mix of Platycladus orientalis leaf extract and alpha-terpineol helps mice grow hair by increasing growth factors and cell growth.
research Single-Cell Analysis Identifies Heterogeneity of Fibroblasts and Myeloid-Derived Adipocytes in Regenerating Mouse Skin Wounds
Fibroblasts and myeloid cells in mouse skin wounds are diverse and can change into different cell types during healing.
research Autoantigen Screening in C3H/HeJ Mouse Model of Alopecia Areata Revealed High Antigenicity of Melanocyte-Associated Antigen Epitopes
Melanocyte-associated antigens may play a key role in alopecia areata and could be targets for new treatments.
research Promotion of Hair Growth in Normal Mouse Skin and Alopecia Areata by Topical Treatment of HDAC Inhibitors
HDAC inhibitors like Vorinostat and Entinostat may encourage hair regrowth and could be new treatments for hair loss conditions.
research Melatonin Receptor MT1 Is Expressed in Mouse Skin and In Vitro Melatonin Treatment Enhances Whisker Growth
Melatonin may help whisker growth in mice.
research Effect of Plant Worm Extract on Mouse Hair Growth
Plant worm extract speeds up hair growth in mice without side effects.
research Quantitative Analysis of Hair Luster in a Novel Ultraviolet-Irradiated Mouse Model
UV exposure reduced hair shine in mice, but minoxidil helped restore it.
research Glucocorticoid Receptor Antagonism Improves Glucose Metabolism in a Mouse Model of Polycystic Ovary Syndrome
Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.
research A Single-Cell RNA Map of Perinatal Developing Mouse Skin
The research mapped gene activity in developing mouse skin and found key markers for skin cell types and changes from fetal to early postnatal stages.
research Spatial Transcriptomic Analysis of Imiquimod-Treated Mouse Skin Reveals Deregulation of Lipid Raft-Associated Markers Reversible by Caveolin Scaffolding Domain Peptide
The research found that a protein called caveolin-1 is reduced in psoriasis, but reintroducing it can help alleviate some psoriasis symptoms.
research Understanding Immune Privilege in an Inducible Mouse Model of Primary Cicatricial Alopecia
The study found that a key immune pathway protecting hair follicles is reduced in a mouse model of scarring hair loss.
research Dissecting the Role of the Common Neurotrophin Receptor CD271 in the Skin: Generation and Characterization of a Novel Mouse Model with Keratinocyte-Specific Conditional Deletion
Deleting the CD271 gene in mouse skin cells leads to disorganized skin and increased hair growth, suggesting CD271 is important for skin health.
research Downregulation of Lhx2 Markedly Impairs Wound Healing in Mouse Fetus
Turning off the Lhx2 gene in mouse embryos leads to slower wound healing and scars.
research The Stem Cell Quiescence and Niche Signaling Is Disturbed in the Hair Follicle of the Hairpoor Mouse, an MUHH Model Mouse
Hair follicle stem cells in hairpoor mice are disrupted, causing hair loss.