Expression of Apoptosis-Related Genes in the Mouse Skin During the First Postnatal Catagen Stage, Focused on Localization of Bnip3L and Caspase-12

June 2015 in “ Connective tissue research ”

Barbora Veselá, Eva Matalová

apoptosis Bnip3L caspase-12 catagen stage hair follicles hair follicle regression hair growth hair loss cell death hair thinning hair shedding

TLDR The research found changes in gene expression related to cell death in mouse skin that help understand hair follicle development and skin health.

The study investigated the expression of apoptosis-related genes in mouse skin during the first postnatal catagen stage, with a focus on the localization of Bnip3L and caspase-12. The researchers found that both Bnip3L and caspase-12 were significantly expressed during this stage, suggesting their involvement in the regulation of apoptosis in hair follicles. The findings provided insights into the molecular mechanisms underlying hair follicle regression and could contribute to understanding hair growth and loss processes.

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