Identification of Bulge Stem Cells in Mouse and Human Hair Follicles

    January 2018 in “ Microscopy research ”
    Bélgica J. Molina, Elda Giansante, Héctor J. Finol
    Studysummary This study found that in identifying bulge stem cells, CD34 is more specific in mice and CD200 in humans, with CD200 potentially marking progenitor and partially differentiated cells.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on scirp.org →
    Discuss this study in the Community →

    Research cited in this study 14

    1. Differential Expression of Stem Cell Markers in Human Follicular Bulge and Interfollicular Epidermal Compartments Histochemistry and Cell Biology · 2010
    2. Stem Cells and the Niche: A Dynamic Duo Cell Stem Cell · 2010
    3. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009
    4. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    5. Multipotent Nestin-Expressing Hair Follicle Stem Cells The Journal of Dermatology · 2009
    6. The Human Keratins: Biology And Pathology Histochemistry and Cell Biology · 2008
    7. Hair Follicle Stem Cells: Walking the Maze European Journal of Cell Biology · 2007
    8. Biology of the Hair Follicle: The Basics Seminars in Cutaneous Medicine and Surgery · 2006
    9. Bulge Cells of Human Hair Follicles: Segregation, Cultivation, and Properties Colloids and Surfaces B: Biointerfaces · 2006
    10. Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005
    11. Location and Phenotype of Human Adult Keratinocyte Stem Cells of the Skin Differentiation · 2004
    12. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003
    13. Manipulation of Stem Cell Proliferation and Lineage Commitment: Visualization of Label-Retaining Cells in Wholemounts of Mouse Epidermis Development · 2003
    14. Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34 Journal of Investigative Dermatology · 2003

    Related research 6

    1. Identification of Bulge Stem Cells in Mouse and Human Hair Follicles Microscopy research · 2018
    2. Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells Journal of Clinical Investigation · 2011
    3. Future Directions: The Known and Unknown Roles of Hair-Follicle Stem Cell Types 2010
    4. The Hair Follicle Stem Cell As The Paradigm Multipotent Adult Stem Cell Springer eBooks · 2008
    5. The Potential of Nestin-Expressing Hair Follicle Stem Cells in Regenerative Medicine Expert Opinion on Biological Therapy · 2007
    6. Multipotent Nestin-Positive, Keratin-Negative Hair-Follicle Bulge Stem Cells Can Form Neurons Proceedings of the National Academy of Sciences · 2005