Identification of Bulge Stem Cells in Mouse and Human Hair Follicles

January 2018 in “ Microscopy research ”

Bélgica J. Molina, Elda Giansante, Héctor J. Finol

hair follicle bulge stem cells cytokeratin 15 CK15 CD34 CD200 immunohistochemical analysis immunofluorescence analysis progenitor cells partially differentiated cells stem cells

TLDR Scientists found markers called CD34 and CD200 that help identify stem cells in mouse and human hair follicles.

The study identified CD34 in mice and CD200 in humans as reliable biomarkers for bulge stem cells in hair follicles, using immunohistochemistry and immunofluorescence. CK15 was less specific. These markers could help isolate and study follicular stem cells, with potential applications in regenerative medicine. The study involved 7 mice and 7 human samples.

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Research cited in this study

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