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GlossaryKeratin 15 (CK15)

protein crucial for hair follicle stem cell regulation

Keratin 15 (K15) is a type of protein found in the hair follicles and skin, playing a crucial role in the structural integrity and function of these tissues. It is particularly important for the maintenance and regeneration of hair, as it is involved in the regulation of stem cells within the hair follicle, which are essential for hair growth and repair.

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research Immunohistochemistry of Canine Hair Follicle Stem Cells Using CK15 and CK19

April 2020 in “Journal of animal research”

Canine hair follicles have stem cells in the bulge region.

research Fluorescence Activated Cell Sorting of CK15 Cells in Canine Hair Follicular Tissue

February 2020 in “International Journal of Current Microbiology and Applied Sciences”

Canine hair follicle cells show stem cell properties, aiding hair growth.

research Cytokeratin 15 Expression in Central, Centrifugal, Cicatricial Alopecia: New Observations in Normal and Diseased Hair Follicles

14 citations , January 2011 in “Journal of Cutaneous Pathology”

CK15 is not a reliable marker for stem cells in damaged hair follicles from patients with CCCA.

research Cytokeratins as Markers of Follicular Differentiation

121 citations , December 2001 in “American Journal of Dermatopathology”

TB and BCC tumors show similar follicular differentiation patterns.

research Stem Cell Markers (Cytokeratin 15, CD34, and Nestin) in Primary Scarring and Nonscarring Alopecia

54 citations , January 2009 in “British Journal of Dermatology”

Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.

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community A Theory on Why Microneedling Works

172 upvotes 6 years ago

Microneedling may enhance hair regrowth by transferring stem cells to dormant follicles, improving the effects of minoxidil. Users discuss using microneedling with needle lengths around 1.5mm to stimulate hair growth.