Itpr3 Is Responsible for the Mouse Tufted (tf) Locus

    October 2012 in “ Journal of Heredity ”
    Hillary T. Ellis, Michael G. Tordoff, M. Rockwell Parker
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    TLDR The Itpr3 gene causes a specific hair pattern in mice.
    The study identified the Itpr3 gene, encoding the inositol triphosphate receptor type 3, as responsible for the tufted (tf) locus in mice, which is associated with a distinctive pattern of hair loss and regrowth, particularly in the BTBR strain. This conclusion was reached through positional cloning methods and complementation mapping.
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