research Adrenal and Gonadal Activity, Androgen Concentrations, and Adult Height Outcomes in Boys With Silver-Russell Syndrome
Higher androgen levels during puberty are linked to shorter adult height in boys with Silver-Russell syndrome.
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450-480 / 789 resultsresearch Independent Genomewide Screens Identify the Tumor Suppressor VTRNA2-1 as a Human Epiallele Responsive to Periconceptional Environment
The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.
research Methylation of CpG Islands in Promoter of Type 2 5-Alpha Reductase and Implications of Finasteride Resistance for BPH Therapy
Methylation in specific gene region causes finasteride resistance in some BPH patients.
research Finasteride Induces Epigenetic Modulation of LSP1: A Gene Implicated in Neutrophil Actin Dysfunction Disease
Finasteride may help treat Neutrophil Actin Dysfunction by reducing LSP1 gene activity.
research Human Epithelial Stem Cell Survival Within Their Niche Requires Tonic Cannabinoid Receptor 1 Signaling—Lessons From the Hair Follicle
Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.
research An Integrated Analysis of Cashmere Fineness lncRNAs in Cashmere Goats
lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.
research Synchronous Profiling and Analysis of mRNAs and ncRNAs in the Dermal Papilla Cells from Cashmere Goats
Non-coding RNAs help control hair growth in cashmere goats.
research Activation of Camp Signaling in Response to Alpha-Phellandrene Promotes Vascular Endothelial Growth Factor Levels and Proliferation in Human Dermal Papilla Cells
α-Phellandrene may help prevent hair loss by increasing growth factors and cell growth in hair cells through a specific signaling pathway.
research Administration of Nrf-2-Modified Hair-Follicle MSCs Ameliorates DSS-Induced Ulcerative Colitis in Rats
Nrf-2-modified stem cells from hair follicles significantly improve ulcerative colitis in rats.
research Molecular Characterization, Expression and Methylation Status Analysis of BMP4 Gene in Skin Tissue of Liaoning Cashmere Goat During Hair Follicle Cycle
BMP4 gene is crucial for hair follicle development in Liaoning cashmere goats.
research Finasteride Induces Epigenetic Alteration of TMPRSS2 Gene Expression: A Potential Role in Severe Acute Respiratory Syndrome Coronavirus 2 Inhibition
Finasteride may help reduce COVID-19 infection by altering a key gene.
research Evidence of Increased DNA Methylation of the Androgen Receptor Gene in Occipital Hair Follicles from Men with Androgenetic Alopecia
Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.
research Association Between DNA Methylation in the Core Promoter Region of the CUT-Like Homeobox 1 (CUX1) Gene and Lambskin Pattern in Hu Sheep
DNA methylation likely doesn't cause different lambskin patterns in Hu sheep.
research Stiffness-Controlled Thermoresponsive Hydrogels for Cell Harvesting with Sustained Mechanical Memory
The hydrogels help harvest cells while preserving their mechanical memory, which could improve wound healing.
research Global Expression Profile and Genome Methylation Signatures in Male Patients with Androgenetic Alopecia
Differences in gene expression and methylation patterns found in AGA patients suggest potential targets for future treatments.
research Characterization of DNA Methylation and Screening of Epigenetic Markers in Polycystic Ovary Syndrome
Altered DNA methylation may be a marker for Polycystic Ovary Syndrome.
research Novel Insights to Assess Climate Resilience in Goats Using a Holistic Approach of Skin-Based Advanced NGS Technologies
Heat stress changes goats' skin and hair at the microscopic level and affects their genes and skin bacteria.
research DNA Dioxygenases Tet2/3 Regulate Gene Promoter Accessibility and Three-Dimensional Chromatin Topology in Lineage-Specific Loci to Control Hair Growth
Tet2 and Tet3 enzymes are essential for controlling hair growth by affecting DNA demethylation and gene expression in mice.
research Dynamics and Epigenetics of the Epidermal Differentiation Complex
Epigenetic mechanisms control skin development by regulating gene expression.
research Acetate Meliorates Depressive-Like Behaviour in a Rat Model of PCOS Through Suppression of HDAC2 Expression and DNA Methylation
Acetate helps reduce depression in rats with PCOS by lowering specific gene expression and DNA changes in the brain.
research Epigenetics and Other Autoimmune Skin Diseases
Epigenetic changes contribute to autoimmune skin diseases.
research Accelerated Aging of Hair Follicles in Androgenetic Alopecia
Hair follicles in androgenetic alopecia age faster, especially in the front.
research Characterization of DNA Methylation and Screening of Epigenetic Markers in Polycystic Ovary Syndrome
DNA methylation changes in women with PCOS could be used as disease markers and suggest new treatment targets.
research Methylated CpG Dinucleotides in 5-Alpha Reductase 2 Gene Might Explain the Finasteride-Resistance in BPE Patients
Methylated gene parts may cause finasteride-resistance in some enlarged prostate patients.
research Non-Histone Methylation of SET7/9 and Its Biological Functions
SET7/9 enzyme affects cell growth and diseases like cancer, diabetes, and obesity.
research Novel Anti-Aging Gene NM_026333 Contributes to Proton-Induced Aging via NCX1 Pathway
The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.
research Signaling Couples Hair Follicle Stem Cell Quiescence With Reduced Histone H3 K4/K9/K27me3 for Proper Tissue Homeostasis
Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
research The Clock Within: Molecular Clock in Epidermis Regulates Circadian Rhythms and Stem Cell Cycles
The circadian clock in skin cells controls their growth and rest cycles.
research DNA Dioxygenases Tet1/2/3 Control Hair Matrix Keratinocyte Differentiation and Hair Shaft Shape via Regulation of Hair Keratin Gene Expression
The enzymes Tet1, Tet2, and Tet3 are important for the development of hair follicles and determining hair shape by controlling hair keratin genes.
research Follicle Dermal Papilla Cells Undergo Chromatin Remodeling Processes In Vivo And In Vitro
Hair follicle cells change their DNA packaging during growth cycles and when grown in the lab.