Characterization of DNA Methylation and Screening of Epigenetic Markers in Polycystic Ovary Syndrome

    May 2021 in “ Frontiers in Cell and Developmental Biology ”
    Pengbo Cao, Weihao Yang, Peijun Wang … Buhe Nashun
    Studysummary This study found that DNA methylation changes in granulosa cells from PCOS patients affect gene expression related to insulin resistance, fat cell differentiation, and steroid metabolism, suggesting an epigenetic contribution to PCOS pathogenesis.
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    Research cited in this study 2

    1. The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report Fertility and Sterility · 2008
    2. Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome (PCOS) Human Reproduction · 2003