The Association Between Polycystic Ovary Syndrome and Its Dermatological Manifestations

February 2020 in “ Cureus ”

Amanpreet Kaur Sekhon, Azka Zergham, Gantuya Tserenpil, Amal Mebasher, Bilal Haider Malik

Polycystic Ovary Syndrome PCOS hirsutism acne seborrheic dermatitis androgenetic alopecia inflammation genetics hormonal imbalances hair loss oily skin genetic factors hormone imbalance

Studysummary This review examines the complex relationship between polycystic ovary syndrome and its associated skin conditions, highlighting an intricate network influenced by hormonal, genetic, and inflammatory factors but reports no new clinical results.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The 2020 study "The Association Between Polycystic Ovary Syndrome and Its Dermatological Manifestations" investigated the relationship between Polycystic Ovary Syndrome (PCOS) and skin conditions such as hirsutism, acne, seborrheic dermatitis, and androgenetic alopecia. The study found that women with PCOS were more likely to experience these dermatological issues, suggesting that these conditions could be potential indicators of PCOS. The relationship between PCOS and these skin conditions was found to be complex, involving factors such as inflammation, genetics, and hormonal imbalances. The study concluded that more research was needed to better understand these relationships and improve the management of PCOS. It also suggested the development of a questionnaire for early diagnosis of PCOS in women presenting with these symptoms.

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Research cited in this study

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research Polycystic Ovarian Syndrome: Correlation Between Hyperandrogenism, Insulin Resistance, and Obesity

195 citations , November 2019 in “Clinica Chimica Acta”

This review discusses the interplay of hyperandrogenism, insulin resistance, obesity, and their role in polycystic ovary syndrome, but presents no new clinical results.

research The Prevalence and Phenotypic Features of Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis

767 citations , September 2016 in “Human Reproduction”

This review analyzes the reported prevalence of polycystic ovary syndrome (PCOS) based on different diagnostic criteria but does not provide new clinical results.

research Correlation of Skin Changes With Hormonal Changes in Polycystic Ovarian Syndrome: A Cross-Sectional Clinical Study

19 citations , January 2015 in “Indian Journal of Dermatology”

In this study, researchers observed that 90% of patients with PCOS had cutaneous manifestations, with acne most common, and found associations between these skin conditions and high insulin or testosterone levels.

research Cutaneous Manifestations of the Subtypes of Polycystic Ovary Syndrome in Korean Patients

16 citations , March 2014 in “Journal of the European Academy of Dermatology and Venereology”

This study found that acne was the most common dermatological manifestation in Korean women with polycystic ovary syndrome, particularly those with a specific combination of symptoms, showing distinct variations in serum hormonal and metabolic parameters.

research Ovarian SAHA Syndrome Is Associated With a More Insulin-Resistant Profile and Represents an Independent Risk Factor for Glucose Abnormalities in Women With Polycystic Ovary Syndrome: A Prospective Controlled Study

28 citations , October 2013 in “Journal of The American Academy of Dermatology”

In this study, ovarian SAHA was found to be independently associated with a more insulin-resistant profile and increased risk of glucose abnormalities in women with PCOS, beyond common risk factors.

research Health Care-Related Economic Burden of Polycystic Ovary Syndrome During the Reproductive Life Span

414 citations , August 2005 in “The Journal of Clinical Endocrinology and Metabolism”

This study estimates the total cost of evaluating and treating polycystic ovary syndrome in reproductive-aged women in the United States to be $4.36 billion, suggesting more liberal screening could be beneficial.

research Bone Morphogenetic Proteins and Their Antagonists in Skin and Hair Follicle Biology

176 citations , January 2003 in “Journal of Investigative Dermatology”

This review summarizes the roles of bone morphogenetic proteins in the development and regulation of normal and diseased skin, but it does not provide new clinical results.