Dermatologic Manifestations of Endocrine Disorders

    October 2017 in “ Translational pediatrics
    Michael Lause, Alisha Kamboj, Esteban Fernández Faith
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    TLDR Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.
    The 2017 review article examines the skin manifestations of various endocrine disorders, highlighting their importance in the diagnosis and management of these conditions. It details how acromegaly, hyperthyroidism, hypothyroidism, diabetes mellitus, Cushing's syndrome, Addison's disease, PCOS, MEN syndromes, and APS present dermatologically. For instance, hypothyroidism can cause cold, dry skin and diffuse alopecia, while diabetes mellitus can lead to conditions like necrobiosis lipoidica diabeticorum. Cushing's syndrome may result in skin atrophy and purple striae. Addison's disease can cause generalized hyperpigmentation, and PCOS may lead to hirsutism and acne vulgaris. MEN syndromes present with various skin lesions, and APS can manifest as chronic mucocutaneous candidiasis. Treatments vary from hormone replacement to lifestyle changes and medications specific to the skin conditions and the underlying endocrine disorder. The paper underscores the necessity of recognizing these dermatologic signs for early detection and intervention of the associated endocrine issues.
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