TLDR PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.
The 2008 document discusses Polycystic Ovary Syndrome (PCOS) in adolescents, highlighting that hormonal abnormalities like hyperinsulinemia and rapid luteinizing hormone (LH) pulse frequency begin in adolescence and contribute to the overproduction of androgens. Hyperandrogenemia (HA) is identified as a central factor in PCOS development, leading to metabolic syndrome, diabetes, and infertility in adulthood. Clinical features such as hirsutism, acne, and menstrual dysfunction are common, with varying prevalence. The paper underscores the importance of early recognition and management of PCOS to prevent long-term complications and discusses treatment options like lifestyle changes, oral contraceptive pills, insulin sensitizers, and antiandrogens. It also calls for more research to identify individuals at risk for HA and its negative outcomes.
50 citations,
February 2007 in “Clinical obstetrics and gynecology” Early detection and treatment of PCOS in teenagers is important to manage symptoms and prevent severe issues.
1744 citations,
August 2006 in “The Journal of Clinical Endocrinology and Metabolism” Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.
414 citations,
August 2005 in “The Journal of Clinical Endocrinology and Metabolism” Polycystic ovary syndrome costs the U.S. over $4 billion a year, mainly from treating related health issues.
947 citations,
February 2004 in “The Journal of Clinical Endocrinology and Metabolism” Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.
39 citations,
September 2000 in “Obstetrics and Gynecology Clinics of North America” Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.
December 2023 in “Frontiers in endocrinology” Excess androgens may cause PCOS, not just be a symptom.
1 citations,
January 2022 in “Journal of experimental and clinical medicine” PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.
12 citations,
July 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” Men with hormonal imbalances similar to PCOS may have increased risk of metabolic and heart diseases.
69 citations,
November 2010 in “Middle East Fertility Society Journal” PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.
76 citations,
January 2007 in “American Journal of Clinical Dermatology” Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.
