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GlossaryAdrenal Insufficiency (Addison's disease)

occurs when adrenal glands produce insufficient cortisol and aldosterone

Adrenal Insufficiency, also known as adrenal failure or adrenal hypofunction, is a condition where the adrenal glands do not produce enough of certain hormones, particularly cortisol and sometimes aldosterone. This can lead to symptoms such as fatigue, muscle weakness, weight loss, low blood pressure, and skin changes. It can be caused by autoimmune disorders, infections, or other underlying health issues, and requires medical diagnosis and management.

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research Rapid Intravenous Administration of Corticotropin as a Test of Adrenocortical Insufficiency

17 citations, August 1967 in “JAMA”

The rapid corticotropin test is a quick and simple way to diagnose adrenal insufficiency.

research Mineral Deficiencies: A Root Cause for Reduced Longevity in Mammals

June 2021 in “IntechOpen eBooks”

Not getting enough minerals can lead to health problems and shorter lifespans.

research Histopathologic Findings of Cutaneous Hyperpigmentation in Addison's Disease and Immunostain of the Melanocytic Population

9 citations, December 2017 in “The American journal of dermatopathology/American journal of dermatopathology”

The study found increased skin pigmentation and variable melanocyte density in a patient with Addison's disease.

research Screening for Associated Autoimmune Disorders in Polish Patients with Addison’s Disease

43 citations, March 2010 in “Endocrine”

research Skin Signs of Systemic Diseases

21 citations, September 2011 in “Clinics in Dermatology”

Looking at skin can help find and treat serious diseases early.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 1 month ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.