TLDR SET7/9 enzyme affects cell growth and diseases like cancer, diabetes, and obesity.
SET7/9, a lysine methyltransferase, methylates both histone and non-histone proteins, influencing cell proliferation, transcription regulation, and protein stability. It is crucial in the development and progression of diseases like hair loss, cancers, atherosclerosis, chronic kidney disease, diabetes, obesity, and pulmonary fibrosis. Its broad substrate range connects it to tumorigenesis and other pathological conditions.
48 citations,
September 2011 in “British Journal of Dermatology” Epigenetic changes in blood cells may contribute to alopecia areata.
13 citations,
December 2014 in “Stem Cells” Hair and skin can regenerate without bulge stem cells due to other compensating cells.
49 citations,
November 2014 in “Journal of Clinical Epidemiology” The objective approach for creating search strategies is as effective as the traditional method and might be better and more efficient.
28 citations,
May 2020 in “BMC plant biology” The study concluded that three enzymes are important for plant development by affecting sugar composition and calcium binding in plants.
883 citations,
August 2016 in “Nature Reviews Disease Primers” Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.
Modern hair restoration techniques can effectively treat hair loss and provide natural-looking results.
