Non-Histone Methylation of SET7/9 and Its Biological Functions
August 2022
in “
Recent patents on anti-cancer drug discovery
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TLDR SET7/9 enzyme affects cell growth and diseases like cancer, diabetes, and obesity.
SET7/9, a lysine methyltransferase, methylates both histone and non-histone proteins, influencing cell proliferation, transcription regulation, and protein stability. It is crucial in the development and progression of diseases like hair loss, cancers, atherosclerosis, chronic kidney disease, diabetes, obesity, and pulmonary fibrosis. Its broad substrate range connects it to tumorigenesis and other pathological conditions.
