DNA Dioxygenases Tet1/2/3 Control Hair Matrix Keratinocyte Differentiation and Hair Shaft Shape via Regulation of Hair Keratin Gene Expression

    June 2020 in “ ˜The œjournal of investigative dermatology/Journal of investigative dermatology ”
    G. Chen, Qiling Xu, Michael Y. Fessing … Vladimir A. Botchkarev
    Studysummary This study found that genetic ablation of Tet genes in mice led to changes in hair structure and keratin gene expression, indicating a role for Tet-mediated 5hmC DNA oxidation in hair follicle development and cycling.
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