September 2024 in “Journal of the American Academy of Dermatology” Dermocosmetics significantly reduce itch and skin sensitivity in atopic dermatitis patients.
This meta-analysis reports that ritlecitinib significantly improved hair growth in alopecia areata patients compared to placebo, although its potential requires further clinical exploration.
March 2024 in “Cancer Research” This meta-analysis found that men with vertex balding at age 40 or older may have a modestly increased risk of prostate cancer, with a pooled relative risk of 1.08, but no significant association was observed with frontal balding.
November 2023 in “Journal of Investigative Dermatology” This research investigated immune cell involvement in various types of inflammatory alopecia by analyzing gene expression data from scalp samples, revealing distinct cellular changes in conditions like Alopecia Areata, Frontal Fibrosing Alopecia, Lichen Planopilaris, and Central Centrifugal Cicatricial Alopecia, which may inform future therapeutic targets.
November 2023 in “Journal of Investigative Dermatology” JAK inhibitors are effective and generally safe for treating alopecia areata, but monitoring for side effects is important.
July 2023 in “The journal of sexual medicine” This study concluded that anabolic-androgenic steroids negatively impact male reproductive health, including reduced testosterone production, impaired sperm production, and increased risk of sexual dysfunction and metabolic issues.
This meta-analysis found that platelet-rich plasma therapy significantly increased hair density in androgenic alopecia, with stand-alone PRP showing notable improvements, but the benefits of combining PRP with other therapies remain uncertain.
January 2023 in “Figshare” This meta-analysis found that a combination of clobetasol, hydroxychloroquine, and N-acetylcysteine may be the most effective treatment approach for lichen planopilaris compared to other therapies.
January 2023 in “Skin appendage disorders” This study concluded that combining 5% minoxidil with microneedling was more effective in improving hair density at 6 months for adults with pattern hair loss compared to other treatments analyzed.
April 2022 in “Research Square (Research Square)” This meta-analysis found that iron deficiency is associated with telogen effluvium and identified critical serum ferritin levels for defining iron deficiency in these patients.
June 2021 in “Research Square (Research Square)” This meta-analysis reported that statins significantly reduced androgen levels and improved skin symptoms in women with polycystic ovary syndrome compared to control treatments.
January 2019 in “Figshare” This study found that intralesional corticosteroids were most likely to produce a response in mild alopecia areata, while diphenylcyclopropenone was top-ranked for moderate to severe cases.
November 2020 in “Journal of The American Academy of Dermatology” This paper discusses photobiomodulation therapy for androgenetic alopecia, focusing on the potential differences in efficacy between laser diodes and LEDs, and reports no new clinical results.
November 2020 in “Journal of The American Academy of Dermatology” Oral health affects overall well-being, with tooth loss impacting quality of life, nutrition, and health.
February 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This meta-analysis reported that dutasteride was more effective than finasteride in increasing hair count and improving visual hair appearance in men with androgenetic alopecia over a 24-week period, while both drugs had similar rates of sexual dysfunction side effects.
308 citations
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December 2018 in “PLOS Genetics” This study identified three novel genetic loci associated with PCOS and found similar genetic architecture across different diagnostic criteria, with evidence suggesting genetic links between PCOS and various metabolic and psychological traits.
2 citations
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May 2018 in “Journal of the American Academy of Dermatology” This meta-regression analysis observed a slightly negative but nonsignificant correlation between vitamin D levels and the severity of alopecia areata, suggesting a complex relationship that requires further investigation.
1250 citations
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August 2021 in “Scientific Reports” In this study, researchers estimated that 80% of patients infected with SARS-CoV-2 experienced at least one long-term symptom, with fatigue being the most common.
767 citations
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September 2016 in “Human Reproduction” This review analyzes the reported prevalence of polycystic ovary syndrome (PCOS) based on different diagnostic criteria but does not provide new clinical results.
223 citations
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June 2018 in “Human Reproduction Update” This study concluded that including ovarian morphology in the diagnosis significantly increases the estimated prevalence of PCOS, revealing substantial variability due to clinical criteria and diagnostic cut-offs.
178 citations
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April 2017 in “Journal of The American Academy of Dermatology” This systematic review and meta-analysis found that minoxidil, finasteride, and low-level laser light therapy significantly improve hair growth in men with androgenetic alopecia, while minoxidil is also effective for women, compared to placebo.
137 citations
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December 2006 in “Arthritis Research & Therapy” This study found that mycophenolate mofetil was associated with higher response rates and lower rates of serious side effects, including a lower mortality rate, compared to cyclophosphamide in lupus nephritis treatment.
128 citations
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February 2016 in “British Journal of Dermatology” This study found that patients with alopecia areata experience significant impairments in health-related quality of life, notably affecting mental health, according to various quality of life assessment tools.
122 citations
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November 2014 in “BMC Medicine” This research observed that oral testosterone replacement therapy significantly increases cardiovascular risk, while effects of injected or transdermal therapy on cardiovascular risk were not significant, prompting further investigation into these methods.
121 citations
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April 2008 in “The Journal of Clinical Endocrinology & Metabolism” Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.
100 citations
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July 2018 in “Journal of The American Academy of Dermatology” This study found that alopecia areata is linked with a higher prevalence of systemic and psychiatric diseases, suggesting that physicians should monitor for these potential comorbidities.
94 citations
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April 2018 in “Nature Genetics” This study identified more than 100 genetic loci associated with hair color variation in Europeans, explaining a significant portion of the trait's heritability and advancing understanding of hair pigmentation.
87 citations
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December 2015 in “Cochrane library” This review observed limited evidence of clinically significant benefits from treatments for acute central serous chorioretinopathy, which often resolves spontaneously, but identified PDT and micropulse laser as the most promising for further trials.
78 citations
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June 2022 in “Infection” Many COVID-19 survivors experience long-term symptoms like fatigue and sleep issues, needing ongoing medical support.
66 citations
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April 2017 in “International Journal of Andrology” This study found that 5α-reductase inhibitors significantly increase the risk of erectile dysfunction and hypoactive sexual desire in men with benign prostatic hyperplasia, compared to placebo.