23 citations
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February 2017 in “Journal of dermatology” This meta-analysis suggests that patients with alopecia areata have lower serum levels of zinc and selenium compared to healthy controls, which may be important risk factors for the condition.
18 citations
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August 2019 in “Clinical breast cancer” This meta-analysis found that in postmenopausal women with a history of breast cancer, 8 weeks of vaginal estrogen therapy while on aromatase inhibitors did not result in systemic absorption of sex hormones, suggesting potential safety for treating vulvovaginal atrophy in this context.
15 citations
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January 2022 in “Journal of Infection” This study's meta-analysis found that COVID-19 vaccines are effective and safe for children, with inactivated vaccines showing the highest effectiveness and causing less injection site pain compared to attenuated vaccines.
10 citations
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June 2024 in “Skin Research and Technology” This meta-analysis found that autologous epidermal cell suspensions reduce healing time, donor site size, operation time, pain scores, and complications in skin lesions. However, their impact on treatment area size, repigmentation, scar scale scores, and patient satisfaction was minimal.
10 citations
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January 2019 in “Advances in Clinical and Experimental Medicine” This meta-analysis reported a significant association between vitamin D receptor gene ApaI polymorphism and polycystic ovary syndrome risk, with variations observed between Asian and Caucasian populations.
9 citations
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December 2018 in “Cutaneous and Ocular Toxicology” This meta-analysis found that combined BRAF and MEK inhibitor treatment in melanoma patients is linked to increased all-grade rash but reduced risks of several other dermatological toxicities compared to BRAF inhibition alone.
8 citations
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May 2025 in “Acta Obstetricia Et Gynecologica Scandinavica” This meta-analysis reported that dienogest and combined oral contraceptives had comparable efficacy and tolerability for endometriosis treatment, with therapeutic choice suggested to be based on patient preference and clinical history.
4 citations
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February 2024 in “Biomedicine” The authors concluded that specific comorbidities and complications increase the risk of severe COVID-19 and impede patient recovery, making them critical factors to control in order to lessen the disease's adverse effects.
2 citations
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July 2023 in “International Journal of Dermatology” This meta-analysis found an increased prevalence of hypothyroidism in patients with lichen planopilaris compared to controls, though the exact relationship between the two conditions remains unclear.
2 citations
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April 2018 in “SLEEP” This meta-analysis found that rheumatoid arthritis patients experience poorer sleep quality compared to healthy controls, including reduced total sleep time and efficiency, longer sleep latency, and increased wakefulness after sleep onset.
Prescription and alternative therapies for hair loss will be compared for effectiveness.
1 citations
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October 2023 in “Journal of plastic, reconstructive & aesthetic surgery” This meta-analysis reported that stem cell-derived conditioned medium effectively increases hair density and thickness in patients with alopecia, with longer treatment durations showing greater improvements.
1 citations
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July 2022 in “Journal of Cataract and Refractive Surgery” This meta-analysis reports that male sex, hypertension, tamsulosin, finasteride, benzodiazepines, and antipsychotics are significantly associated with increased risk of developing intraoperative floppy-iris syndrome during cataract surgery.
1 citations
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November 2021 in “Translational pediatrics” This meta-analysis reported no significant improvement in muscle strength or mobility with glucocorticoid treatment for progressive muscular dystrophy but observed an increase in adverse effects like acne and emotional irritability.
June 2026 in “Skin Appendage Disorders” This meta-analysis found that GLP-1 receptor agonists are associated with a 40% increased risk of non-scarring alopecia, likely due to weight loss-induced micronutrient deficiency, with significant associations for telogen effluvium and androgenetic alopecia. However, some patients with central centrifugal cicatricial alopecia showed improvement.
May 2026 in “Journal of Cosmetic Dermatology” This meta-analysis found that fractional laser therapy significantly improved hair density in patients with androgenetic alopecia and exhibited a favorable safety profile, with mild to moderate adverse events. Combination therapy with laser and other treatments was more effective than other treatments alone.
February 2026 in “European journal of medical research” This study found that combination therapy with alpha-adrenergic blockers and 5α-reductase inhibitors significantly improved urinary symptoms, reduced prostate volume, and decreased the risk of acute urinary retention and postoperative surgery in patients with benign prostatic hyperplasia compared to monotherapy.
January 2026 in “BMC Public Health” This meta-analysis found that several factors are significantly associated with the presence and progression of androgenetic alopecia, including family history, smoking, alcohol consumption, poor sleep quality, being overweight, hypertension in men, insulin resistance, and high fasting insulin levels.
October 2025 in “Figshare” This meta-analysis found that deuruxolitinib significantly improved hair regrowth and patient satisfaction in those with moderate to severe alopecia areata compared to placebo, though it was associated with manageable side effects such as elevated creatinine kinase levels, headaches, and acne, especially at higher doses.
October 2025 in “Figshare” This systematic review and meta-analysis reported that deuruxolitinib is effective for hair regrowth and improving patient-reported outcomes in individuals with moderate to severe alopecia areata, but observed manageable treatment-emergent adverse events such as elevated creatinine kinase levels and headaches, particularly with higher doses.
September 2025 in “Figshare” This study conducted a scoping review and meta-analysis revealing a complex chemokine profile in alopecia areata patients, with elevated Th1, Th2, and other immune pathway chemokines, suggesting broader immunomodulatory strategies may help address the disease's multifaceted immune dysregulation.
September 2025 in “Figshare” In this scoping review and meta-analysis, researchers found that patients with alopecia areata exhibit complex chemokine profiles, with elevated levels of Th1, Th2, and other immune pathway-associated chemokines, suggesting the potential for broad immunomodulatory strategies to address the disease's immune dysregulation.
August 2025 in “Figshare” This meta-analysis found that patients with alopecia areata, especially those with alopecia totalis or alopecia universalis, have an increased risk of cardiovascular disease, possibly due to shared immunological mechanisms and systemic inflammation. Further research is needed to confirm these findings and explore underlying mechanisms.
August 2025 in “Figshare” This meta-analysis found that patients with alopecia areata, especially those with more severe forms like alopecia totalis or universalis, may have an increased risk of cardiovascular disease, suggesting a potential link between the systemic inflammation in AA and cardiovascular risk.
July 2025 in “Derecho y cambio social.” This cross-meta-analysis examined policosanol biorefining methods in 18 Ibero-American countries, reporting that Cuba, Spain, Brazil, Chile, Mexico, and Portugal show significant advances, but highlighted the need for better coordination between academia and industry for improved yield efficiency.
February 2025 in “International Journal of Molecular Sciences” This meta-analysis of animal studies found that alkaloids have potential anti-influenza and anti-inflammatory effects, correlating with improved viral titers and survival rates, though they did not effectively reduce TNF-α and IL-6 levels. Extensive further studies are needed to confirm these findings before considering clinical application.
January 2025 in “Dermatologic Surgery” This meta-analysis and systematic review found that botulinum toxin injections significantly increased hair count in patients with androgenetic alopecia compared to controls, indicating promising efficacy and good safety.
January 2025 in “Figshare” This meta-analysis concluded that compound glycyrrhizin combined with conventional treatments enhanced hair regrowth in alopecia areata patients, though it was associated with some mild adverse effects like oedema.
January 2025 in “Figshare” This meta-analysis concluded that compound glycyrrhizin combined with conventional treatments improved hair regrowth in patients with alopecia areata, though it was associated with mild adverse events like edema.
November 2024 in “International Journal of Scientific Reports” This meta-analysis found that while both Dienogest and GnRH analogues effectively managed endometriosis-related pain, Dienogest reduced recurrence rates and hot flushes but increased irregular bleeding, making it a safer option due to fewer side effects.