August 2025 in “International Journal of Molecular Sciences” This meta-analysis found that among topical OTC treatments for male androgenetic alopecia, minoxidil 5% applied twice daily was the most effective in increasing total hair density over 24 weeks.
August 2025 in “Frontiers in Immunology” This meta-analysis found that patients with alopecia areata, particularly those with more extensive forms like alopecia totalis and universalis, may face a higher risk of cardiovascular disease, though no links were found with specific conditions like ischemic stroke or myocardial infarction.
September 2024 in “Journal of the American Academy of Dermatology” This meta-analysis found that smoking is significantly associated with increased odds of developing and progressing androgenetic alopecia, with higher risks observed in men smoking at least 10 cigarettes daily.
July 2024 in “Journal of Investigative Dermatology” JAK inhibitors improve hair growth in alopecia areata, especially in patchy types.
This study reported that Sintilimab combined with chemotherapy may improve outcomes in advanced NSCLC patients but carries a higher risk of certain side effects, including hypothyroidism.
This research review found that spironolactone can significantly improve acne severity more effectively than a placebo, with 73.3% of patients reporting satisfaction despite a 26.7% rate of adverse events among the 1,548 participants studied.
This research aims to evaluate 6-month changes in total and terminal hair density, with data quality assessed using Cochrane risk of bias tools, but does not report specific study results yet.
January 2024 in “Journal of Cosmetic Dermatology” This study found that men who smoke are more likely to develop androgenetic alopecia and experience disease progression compared to non-smokers.
January 2024 in “Gynecologic and Obstetric Investigation” This meta-analysis reported no significant differences in vocal alterations and quality of life between women with PCOS and control groups, yet emphasized that the findings are limited by a lack of high-quality studies, suggesting further research is needed.
December 2023 in “Migration letters” This meta-analysis reviewed 25 studies and suggested that herbal interventions could improve reproductive health in women with PCOS, showing benefits across measures such as Body Mass Index, hirsutism, and insulin levels, although results were mixed for fasting glucose and FSH levels.
August 2023 in “Aesthetic Plastic Surgery” This meta-analysis found that PRP monotherapy improved hair density in androgenetic alopecia patients but did not affect hair diameter, with stronger effects observed in male subjects.
November 2022 in “Research Square (Research Square)” This meta-analysis suggests a significant association between the use of facial sunscreen and moisturizer and frontal fibrosing alopecia, while finding no significant relationship with hair products or treatments.
May 2022 in “Clinical Epigenetics” This study found that maternal early-pregnancy serum ferritin concentrations were associated with lower DNA methylation levels at specific CpG sites in cord blood, with some associations persisting into childhood.
March 2023 in “Research Square (Research Square)” This meta-analysis suggests that combining minoxidil with microneedling significantly increases total hair count compared to minoxidil alone in patients with androgenetic alopecia, although it did not significantly affect hair diameter.
March 2020 in “Journal of Laser Applications” This meta-analysis reported that photobiomodulation therapy may improve hair density and stimulate hair growth in patients with androgenic alopecia compared to sham treatments, but larger studies are needed to confirm these findings.
62 citations
,
July 2017 in “Endocrine connections” This meta-analysis reported a significant association between polycystic ovary syndrome and an increased risk of obstructive sleep apnea in adult patients.
41 citations
,
October 2011 in “Clinical and Experimental Dermatology” This meta-analysis suggests that the G allele of AR StuI polymorphism might be a potential risk factor for AGA, particularly in white populations.
19 citations
,
March 2022 in “Journal of Infection” This article discusses the withdrawal of bamlanivimab monotherapy's emergency use authorization in the U.S. due to evolving COVID-19 variants and offers no new clinical data.
13 citations
,
September 2022 in “Biomolecules” This study found that specific gene upregulations and mutations in hidradenitis suppurativa skin support the role of inflammation, altered epithelial differentiation, and metabolism dysregulation in the disease's pathogenesis.
10 citations
,
June 2024 in “Frontiers in Genetics” This study analyzed RNA-seq data from various animal breeds and suggested that similar molecular mechanisms may underlie wool fineness in different sheep breeds. Researchers identified 32 candidate genes related to hair follicle regulation, providing insights for molecular breeding and evolutionary studies.
2 citations
,
October 2025 in “Frontiers in Medicine” This study found that deuruxolitinib may effectively improve hair regrowth and patient satisfaction in moderate to severe alopecia areata, but careful monitoring is needed due to manageable side effects and concerns about long-term safety.
2 citations
,
January 2019 in “BMC Cancer” This meta-analysis suggests that any pattern of male baldness may be associated with a decreased risk of testicular cancer, with stage II hair loss providing the strongest protective effect.
January 2026 in “Dermatologic Therapy” In this systematic review and meta‐analysis, botulinum toxin monotherapy was found to significantly increase hair density in patients with androgenetic alopecia, with optimal effects observed using a 100-unit dose every six months. These findings suggest potential efficacy but should be confirmed in larger, placebo-controlled trials.
October 2025 in “International Journal of Molecular Sciences” This study identified changes in immune activation, ferroptosis, and structural genes in alopecia areata subtypes, suggesting molecular markers that might help understand disease variability and guide future treatments.
October 2024 in “International Journal of Dermatology” In this meta-analysis, researchers found that oral and topical minoxidil treatments for androgenetic alopecia had similar efficacy in improving hair density and diameter, but oral minoxidil resulted in a higher incidence of hypertrichosis compared to topical use.
January 2024 in “International Wound Journal” Combination antibiotic therapy is more effective but causes more side effects.
September 2023 in “Journal of the American Academy of Dermatology” This meta-analysis found a significant positive association between frontal fibrosing alopecia and both sunscreen and moisturizer use, with the moisturizer association significant only in males.
April 2023 in “Journal of Investigative Dermatology” This study found that adults with atopic dermatitis who were treated with baricitinib at doses of 2mg or 4mg experienced significant improvements in work productivity, potentially leading to substantial indirect cost savings for employers over 16 weeks.
91 citations
,
December 2017 in “Systems Biology in Reproductive Medicine” This meta-analysis found that lower serum SHBG levels are associated with an increased risk of PCOS, and improving SHBG levels through treatment may reduce PCOS complications.
31 citations
,
October 2015 in “DOAJ (DOAJ: Directory of Open Access Journals)” This meta-analysis found that the prevalence of PCOS among Iranian women varies by diagnostic criteria, with notable rates of associated complications like hirsutism, acne, and menstrual disorders.