The Efficacy of Botulinum Toxin in the Treatment of Androgenetic Alopecia: A Meta-Analysis
January 2026
in “
Dermatologic Therapy
”
New to Botox? There is a guide in the encyclopedia. Read the guide → Studysummary In this systematic review and meta‐analysis, botulinum toxin monotherapy was found to significantly increase hair density in patients with androgenetic alopecia, with optimal effects observed using a 100-unit dose every six months. These findings suggest potential efficacy but should be confirmed in larger, placebo-controlled trials.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
This meta-analysis evaluated 7 studies with 232 participants and found that Botulinum Toxin (BTX) significantly increased hair density and diameter in patients with androgenetic alopecia (AGA). The optimal injection dose was 100 U, with reinjections every 6 months showing significant improvements, particularly in male participants. Despite high-quality evidence and consistent results, limitations included small sample sizes and high heterogeneity. The study suggests BTX as a promising treatment for AGA, but emphasizes the need for large-scale randomized controlled trials to establish standardized treatment protocols.
