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Different types of skin fibroblasts have unique roles in skin health and disease.

Light affects skin health, aging, and cancer risk, and new light-based treatments and imaging are promising for skin care.

Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.

Hair proteins in preschool children and their mothers could indicate developmental changes and health status.

The article concludes that creating a detailed map of normal human skin at the single-cell level is important.

Human skin xenografting could improve our understanding of skin development, renewal, and healing.

Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.

Cannabis may help with skin and hair health but could also increase heart and stroke risks.

Genetically repaired stem cells may treat certain genetic diseases, Th17 cells are key in fighting systemic fungal infections, hair loss in AGA is due to progenitor cell loss, and α-synuclein transfer might contribute to Parkinson's disease progression.

Central lipohypertrophy in HIV-infected women may lead to shorter eyelashes.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

Improving dermal papilla cells can help regenerate hair follicles.

Finasteride worsens heart damage from nandrolone decanoate but protects against cell damage.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Nanoparticles can deliver vaccines through hair follicles, triggering immune responses and providing protection.

Metabolic signals and cell shape influence how cells develop and change.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.

The project created a standardized system for classifying skin lesions in lab rats and mice.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

Sirtuin 1 could be a potential drug target for treating hypertrophic scars.

Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.

Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.