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    Glossary Keratinization Disorders

    abnormal keratin production causing skin, hair, and nail issues

    Keratinization disorders are conditions where the process of keratinization, the formation of the protein keratin in the skin, hair, and nails, is abnormal. This can lead to symptoms like thickened skin, scaling, and other skin abnormalities. Examples include psoriasis and ichthyosis, where the skin cells produce too much keratin or shed improperly, causing visible and sometimes uncomfortable skin changes.

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      Disorders of Keratinization

      research Disorders of Keratinization

      November 2014
      This chapter reviews various skin disorders classified as Mendelian disorders of cornification and reports no new clinical findings, highlighting the complexity of genetics involved in inherited ichthyoses.

      research Keratinization and its Disorders

      95 citations , September 2012 in “Oman Medical Journal”
      This review discusses the structure, types, and distribution of keratins and their role in tissue fragility disorders, particularly within the oral cavity, without presenting new clinical findings.

      research Disorders of Keratinization

      44 citations , January 2004 in “American journal of clinical dermatology”
      This review covers various disorders of cornification and their treatments, offering clinical insights but reporting no new research findings.
      Psoriasis, Acne, and Disorders of Keratinization

      research 11. Psoriasis/Acne and Disorders of Keratinization

      July 2003 in “Journal of Cutaneous Medicine and Surgery”
      Treating psoriasis with UVB light three times a week is faster than twice a week, and certain medications and lifestyle factors affect psoriasis treatment outcomes.

      research Retinoids and Keratinization

      32 citations , March 1988 in “International Journal of Dermatology”
      This review discusses current concepts on the role of retinoids in keratinization and does not report new clinical results; the authors emphasize the complexity of retinoid effects on skin.

      research Follicular porokeratosis: four new cases

      6 citations , July 2017 in “Clinical and Experimental Dermatology”
      This report presents four new cases of follicular porokeratosis, which exhibit distinct histological features where the cornoid lamella are confined to the follicular ostia.

      research Olmsted syndrome

      2 citations , June 2013 in “Journal of Dermatological Case Reports”
      This article presents a case of Olmsted syndrome in a 5-year-old boy, adding to the limited number of reported cases of this rare keratinization disorder.

      research Ulerythema ophryogenes (keratosis pilaris atrophicans faciei).

      September 2016 in “European Journal of Pediatric Dermatology/PD. European journal of pediatric dermatology”
      This article discusses the characteristics and challenges of treating ulerythema ophryogenes, noting the limited effectiveness of emollients, vitamin A, retinoids, and transient response to corticosteroids, with some success using dye laser therapy.
      Novel Drugs Targeting Retinoic Acid Receptors

      research Novel Drugs Targeting Retinoic Acid Receptors

      January 2005
      This article reviews different generations of synthetic retinoids for dermatological use, discussing their efficacy and significant side effects, but reports no new clinical results.
      Congenital and Hereditary Skin Diseases in Bovines

      research Congenital and Hereditary Skin Diseases

      January 2018
      This chapter reviews various fungal skin diseases affecting cattle but does not report new research findings; it focuses on rare, inherited, and congenital conditions like follicular dysplasia and cutaneous asthenia.

      research Ichthyoses

      January 2015 in “Springer eBooks”
      Ichthyoses are skin disorders causing scales, with treatment depending on type and severity.
      Learning From Nudity: Lessons From The Nude Phenotype

      research Learning from nudity: lessons from the nude phenotype

      86 citations , October 2005 in “Experimental Dermatology”
      This review explores the role of Foxn1 in mammalian skin biology, discussing its influence on hair follicle function and the potential for further research to enhance understanding of epithelial differentiation.
      Preface

      research PREFACE

      October 1996 in “Dermatologic Clinics”
      Research on hair disorders has advanced, with promising future progress in understanding and treating these conditions.
      Zinc and Zinc Transporters in Dermatology

      research Zinc and Zinc Transporters in Dermatology

      4 citations , December 2022 in “International Journal of Molecular Sciences”
      This review discusses the role of zinc and its transporters in skin health and disorders, providing an overview without presenting new clinical results.

      research HAIR KERATINIZATION IN HEALTH AND DISEASE

      22 citations , October 1996 in “Dermatologic clinics”
      This review summarizes recent advances in understanding intermediate filament structure and their implications for pathological mutations and human diseases, but it reports no new experimental results.
      Loose Anagen Hair as a Cause of Hereditary Hair Loss in Children

      research Loose Anagen Hair as a Cause of Hereditary Hair Loss in Children

      55 citations , October 1992 in “Archives of Dermatology”
      In this study, researchers observed that loose anagen hair syndrome is an autosomal dominant disorder characterized by abnormal hair follicle structure and premature keratinization, possibly due to signaling and desmosomal component disturbances.
      Do You Know This Syndrome? Loose Anagen Hair Syndrome in a Two-Year-Old Male Patient

      research Do you know this syndrome? * Você conhece esta síndrome? *

      January 2006
      This review discusses loose anagen hair syndrome, a benign and self-limited condition predominantly affecting children, and highlights the importance of differentiating it from other hair disorders like telogen effluvium and trichotillomania, but reports no new results.
      Keratosis Pilaris Is a Keratinization of Hair Follicles

      research Keratosis Pilaris Is a Keratinization of Hair Follicles

      March 2023 in “International journal of integrated medical research”
      This article discusses keratosis pilaris, a common skin condition often considered a normal variant, and reviews its associations, progression, and available treatments without reporting new clinical results.
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