TLDR Thyroid hormone may be useful for treating various skin conditions and needs more research.
The document from 2008 discusses the potential of thyroid hormone as a treatment for various skin conditions, including disorders of keratinization, alopecia, wound healing, xerosis, and chronic idiopathic urticaria. It highlights the presence of thyroid hormone receptors in skin tissues and the hormone's direct action on these tissues. Animal studies have shown that topical thyroid hormone can stimulate epidermal proliferation, dermal thickening, and hair growth, while in humans, it has been used to accelerate wound healing and treat xerosis. The authors argue that the therapeutic potential of thyroid hormone for skin pathology is significant and calls for more research. They also mention a conflict of interest, as one author holds a patent for the use of topical thyroid hormone in treating xerosis.
111 citations,
April 2000 in “British journal of dermatology/British journal of dermatology, Supplement” Thyroid hormone receptor β1 is found in human hair follicles and helps them survive.
12 citations,
October 1995 in “The Journal of Clinical Endocrinology & Metabolism” Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.
116 citations,
December 2017 in “International Journal of Women's Dermatology” Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.
46 citations,
July 1988 in “Journal of The American Academy of Dermatology” Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.
9 citations,
July 2020 in “Experimental Dermatology” Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
136 citations,
April 2010 in “British Journal of Dermatology” Acitretin is effective for severe skin conditions but has significant side effects and requires careful monitoring.
