Topical Thyroid Hormone Accelerates Wound Healing in Mice
June 2005
in “
Endocrinology
”
Studysummary This study found that applying supraphysiologic doses of topical T3 significantly accelerated wound healing in mice compared to a control vehicle, suggesting its potential as a cost-effective wound treatment.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The study investigated the effects of topical application of supraphysiologic doses of T3 on wound healing in mice. Mice with 10-mm diameter dorsal skin wounds were treated with 150 ng of T3 daily, resulting in 58% greater wound closure compared to when the same mice received a vehicle alone. The study also found that T3 treatment increased keratin 6 protein expression in hair follicle keratinocytes in a dose-dependent manner. These findings suggested that T3 played a significant role in enhancing wound healing and could potentially be used as an inexpensive treatment to accelerate the healing of certain wounds.
