1 citations
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March 2023 in “Tidsskrift for Den norske lægeforening” Keratosis pilaris is a common skin condition causing a bumpy texture, sometimes linked to other diseases, with various treatments available.
1 citations
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November 2022 in “International journal of trichology” A girl with a rare skin condition improved after one month of treatment with acitretin.
480 citations
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August 2014 in “Nature Biotechnology” Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
186 citations
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December 2012 in “Current opinion in cell biology” Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
95 citations
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September 2012 in “Oman Medical Journal” The document reviewed the structure and function of keratins, which are structural proteins crucial for maintaining the integrity of keratinocytes. It highlighted that humans have around 30 keratin families, divided into acidic and basic groups, with 54 functional genes coding for them. These keratins are expressed in specific patterns depending on epithelial type and differentiation stage. Mutations in keratin genes were linked to tissue fragility disorders affecting skin and mucosa. Keratins serve as differentiation markers, with antibodies to keratin aiding in diagnostic pathology. The review also focused on keratinization disorders, particularly in the oral cavity, and noted the clinical significance of keratin.
185 citations
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December 2010 in “Archives of Biochemistry and Biophysics” Keratin gene mutations cause various skin and hair disorders, but new research offers hope for future treatments.
253 citations
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April 2008 in “Current opinion in cell biology” Notch signalling helps skin cells differentiate and prevents tumors.
153 citations
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October 2007 in “Cell Stem Cell” New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
508 citations
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February 2007 in “Cell” Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
686 citations
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February 2002 in “Current Opinion in Cell Biology” Keratin filaments are crucial for cell structure and protection, with ongoing discoveries about their genes and functions.
