TLDR Retinoids can help treat skin disorders by improving the skin's outer layer.
The document "Retinoids and Keratinization" from 1988 reviewed the role of retinoids, derivatives of vitamin A, in the process of keratinization, which is the formation of the protective outer layer of the skin. It discussed how retinoids influenced the differentiation and proliferation of keratinocytes, the primary cell type in the epidermis, and highlighted studies showing that retinoids could modulate epidermal cell growth, enhance the production of specific keratins, and affect the structural integrity of the skin. The review underscored the potential therapeutic applications of retinoids in treating skin disorders characterized by abnormal keratinization, such as psoriasis and ichthyosis.
52 citations,
June 1981 in “International Journal of Dermatology” Oral retinoids are effective for severe skin conditions but require careful use due to side effects.
40 citations,
January 2016 in “Elsevier eBooks” The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
January 2021 in “Acta Scientiae Veterinariae” Levothyroxine effectively treated a dog's skin and hair problems caused by hypothyroidism.
1 citations,
June 2017 in “Veterinary dermatology” A cross-bred lamb with severe skin and movement issues had ichthyosis fetalis but normal vitamin A levels.
January 2019 in “ARC journal of pharmaceutical sciences” Acne can be managed with various treatments and requires psychological support due to its emotional impact.
18 citations,
June 2019 in “Clinical research in dermatology” Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.
12 citations,
September 2003 in “Current paediatrics” Early treatment of acne is important to prevent scarring and improve appearance, using medications that can have side effects.