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    GlossaryKeratosis Follicularis

    rare genetic skin disorder causing rough, warty papules and plaques

    Keratosis Follicularis, also known as Darier's Disease, is a rare genetic skin disorder characterized by the development of rough, warty papules and plaques, primarily in seborrheic areas such as the scalp, forehead, upper arms, chest, and back. It is caused by mutations in the ATP2A2 gene, which affects calcium regulation in skin cells, leading to abnormal keratinization and skin cell adhesion.

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      community My skin is always dry and flakes like chalk (25)

      in Transgender  6 upvotes 8 months ago
      The user underwent a biopsy two years ago and was diagnosed with keratosis pilaris, leading to hair issues. They tried treatments including Minoxidil, betamethasone, lymecycline, topical Accutane, and dutasteride, as well as diet changes, without improvement in hair thickness or skin dryness.

      community What are these spots on my scalp

      in Treatment  51 upvotes 5 months ago
      A user noticed non-itchy, non-bleeding spots on their scalp while experiencing hair loss. Replies suggest the spots are likely sunspots or liver spots and recommend seeing a dermatologist; hair loss is attributed to male pattern baldness.

      community My Experience and a Discourse on "DUPA"

      in Treatment  9 upvotes 6 months ago
      The user discusses their hair loss experience, exploring various hypotheses including thyroid levels, vitamin D, DHEA, nutritional deficiency, diabetes, seborrheic dermatitis, lack of nutrition to hair follicles, chronic inflammation, female pattern hair loss causes, cortisol, and prolactin levels. They are currently using finasteride, beta-sitosterol, and have tried topical dutasteride and microneedling therapy.

      community The hardest hair protocol ever!

      in Research/Science  10 upvotes 2 years ago
      The user is using RU58841, finasteride, dutasteride, and minoxidil to slow down aggressive hair loss but is still experiencing hair shedding due to high testosterone levels. They plan to use ostarine to lower testosterone and prevent hair loss while maintaining muscle mass, and will continue using the other treatments.