TLDR Ichthyoses are skin disorders causing scales, with treatment depending on type and severity.
The document "Ichthyoses" described a group of Mendelian disorders of keratinization, characterized by the presence of scales on the skin. These disorders could appear at birth or later and might be isolated or associated with other anomalies. Treatment varied based on the type of ichthyosis, patient age, affected areas, and disease extent. The document also included abbreviations for specific genes related to ichthyoses and referenced various studies and treatments, highlighting the complexity and variability in managing these conditions.
The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.
November 2023 in “Frontiers in pharmacology” Drug repositioning offers hope for new, affordable treatments for a genetic skin disorder called ARCI.
47 citations,
March 2016 in “Journal of dermatology” Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.
Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.
10 citations,
July 2015 in “Current opinion in pediatrics, with evaluated MEDLINE/Current opinion in pediatrics” New genes linked to ichthyosis were found, but there's still no cure; treatment options are improving.
