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Glossary scales

small, plate-like structures covering skin or dry, flaky patches

Scales refer to the small, plate-like structures that cover the skin of certain animals, such as fish and reptiles, providing protection and reducing water loss. In the context of human biology and dermatology, scales can also describe the flaky, dry patches of skin that result from conditions like psoriasis or eczema, where the outer layer of skin cells accumulates and sheds abnormally.

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Research

5 / 1000+ results

research Dermo‐epidermal interactions in reptilian scales: Speculations on the evolution of scales, feathers, and hairs

38 citations , July 2004 in “Journal of experimental zoology. Part B, Molecular and developmental evolution”

This article discusses a hypothesis on the development and evolution of scales, hairs, and feathers from fish to amniotes, based on regions of dermo-epidermal interactions in skin, but reports no new findings.

research cDermo-1 misexpression induces dense dermis, feathers, and scales

29 citations , December 2004 in “Developmental biology”

In this study, forced expression of the transcription factor cDermo-1 in chicken dermis led to the formation of ectopic feather buds and enhanced feather growth, demonstrating its role in initiating skin appendage development.

research Beyond health-related quality of life: initial psychometric validation of a new scale for addressing the gap in assessing the full range of alopecia areata psychosocial burden

8 citations , June 2023 in “British Journal of Dermatology”

This study developed and initially validated the Scale of Alopecia Areata Distress (SAAD), a 41-item tool designed to measure psychosocial distress among US adults with alopecia areata.

research Classification scale for male and female androgenetic alopecia.

6 citations , February 1996 in “Clinical Pharmacology & Therapeutics”

Scale created to measure hair loss in men and women; MK-386 reduces acne; Niaspan treats dyslipidemia; minoxidil increases heart rate.

research Scale-Up of a Medicinal and Aromatic Plant-Based Shampoo Formulation: Physicochemical Quality, Microbiological Safety, and Stability Analyses

July 2026 in “Journal of Apitherapy and Nature”

This study evaluated a plant-based shampoo formulation's scale-up from laboratory to industrial production, reporting that the product maintained its quality, safety, and stability at each scale while meeting microbiological safety standards.

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Community Join

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community I scaled my company to +100k MRR and became bald in the process. (I’m 24)

204 upvotes 5 months ago

A 24-year-old scaled his company to over $100k MRR but experienced hair loss, attributing it to stress and genetics despite using treatments like Dutasteride and Minoxidil. Many suggest embracing baldness, focusing on health, or considering additional treatments like Finasteride, while others debate the impact of stress versus genetics on hair loss.

community Norwood scale ? 28m

in General 68 upvotes 1 year ago

A 28-year-old is assessing their hair loss on the Norwood scale, considering adding topical minoxidil and dermastamping to their current regimen of oral finasteride and minoxidil. They feel their hair loss is worsening and seek opinions on their condition.

community A new study by Deng and colleagues set out to explore differences between balding and non balding scalps...

39 upvotes 4 years ago

Balding scalps have more androgen receptors, leading to increased TGF-beta, which causes blood vessel loss and hair follicle miniaturization. Blocking androgen signaling and TGF-beta may help prevent hair loss.

community These yellow scales will be the death of me. Anyways I’m f’ed up

in Treatment 145 upvotes 8 months ago

Managing seborrheic dermatitis using ketoconazole shampoo, Nizoral, and oils like MCT and coconut oil. The user considers shaving their head and consulting a dermatologist.

community 31M: Assessing Norwood Scale After 8 Days Growth & Past Finasteride Use

in General 114 upvotes 8 months ago

A 31-year-old male considering returning to finasteride at a lower dose or using topical finasteride to assess his Norwood scale for a potential future hair transplant. He previously stopped finasteride due to side effects and has been shaving his head.

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Learn

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learn capsicum

Is capsicum safe for sensitive scalps or inflammatory hair loss? Capsicum may irritate sensitive scalps and worsen inflammatory hair loss.

learn Hair Fibers

Are hair fibers safe for sensitive scalps or people with dandruff and irritation? No study has tested hair fibers on sensitive or dandruff-prone scalps. Users are advised to wash them out daily, try a small area first, and stop if irritation appears.

learn Ecklonia Cava

Is Ecklonia Cava safe for sensitive or irritated scalps? No published study has tested Ecklonia cava on sensitive or irritated human scalps. Any botanical extract can cause irritation or allergy, so patch-test first and stop if irritation occurs.

learn oleic acid

Can Oleic Acid help with dry or irritated scalps that lead to hair loss? Oleic acid-rich oils may feel moisturising, but oleic acid loosens the skin barrier and can trigger flaking in dandruff-prone people. No trial shows it helps scalp-related hair loss.

learn Salicylic acid

Is it safe to use salicylic acid on sensitive or irritated scalps? Salicylic acid can irritate a sensitive or broken scalp. People allergic to aspirin should not use it, and rare poisoning has been reported after use on large areas of skin.

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