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    Glossary Hyperkeratinization

    excessive keratin production leading to thickened skin patches

    Hyperkeratinization is a condition where there is an excessive production of keratin, a protein that helps form the outer layer of the skin, hair, and nails. This overproduction can lead to the thickening of the skin and the formation of rough, scaly patches, and is often associated with conditions like acne, psoriasis, and certain types of alopecia.

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    Research 10 of 235

    1. Updated Treatment for Acne: Targeted Therapy Based on Pathogenesis Dermatology and Therapy · 2021 · 78 citations
    2. Pathways to inflammation: acne pathophysiology European Journal of Dermatology · 2011 · 68 citations
    3. Zinc Deficiency in Suckling Mice Deprived of Colostrum 1953 · 53 citations
    4. Meibomian gland changes in the rhino (hrrhhrrh) mouse. PubMed · 1988 · 48 citations
    5. Fibroblast growth factor and epidermal growth factor in hair development 1993 · 39 citations
    6. The evolution of healthy skin to acne lesions: a longitudinal, <i>in vivo</i> evaluation with reflectance confocal microscopy and optical coherence tomography Journal of the European Academy of Dermatology and Venereology · 2019 · 19 citations
    7. No evidence for follicular keratinocyte hyperproliferation in acne lesions as compared to autologous healthy hair follicles Experimental Dermatology · 2018 · 7 citations
    8. Acne Syndromes and Mosaicism Biomedicines · 2021 · 1 citations
    9. Clinical Management of Vitamin A Responsive Dermatosis in a Labrador Retriever Dog The Indian Veterinary Journal · 2025
    10. 5-Bromo-2′-deoxyuridine induced effluvium via p53-mediated CD326-positive keratinocyte apoptosis in C57BL/6 mice Journal of Dermatology · 2016
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