10 citations
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May 1986 in “Experientia” This animal study found that second generation mice exposed to excess zinc during gestation and lactation had reduced plasma copper, body weight, and hematocrit, with lighter and delayed hair development compared to mice on a normal zinc diet.
50 citations
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November 1984 in “Journal of Heredity” This study found that supplementing zinc improved certain developmental defects in mice with the lethal-milk mutation, although it did not increase the survival rate among backcross progeny.
December 2023 in “Journal of nutritional science and vitaminology” This study in mice found that a zinc-deficient diet suppressed body weight gain and increased kidney and cecum tissue weight without decreasing serum alkaline phosphatase activity. Additionally, zinc deficiency caused alopecia and intestinal changes in C57BL/6J mice, potentially affecting nutritional status.
4 citations
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January 1992 in “The Tohoku Journal of Experimental Medicine” In this study, chronic zinc chloride administration in mice led to the replacement of long coarse hairs with short fine hairs, while overall skin histology remained normal.
45 citations
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June 1984 in “Journal of the American Veterinary Medical Association” In this study, zinc supplementation rapidly improved conditions such as anorexia, depression, and foot soreness in sheep and goats diagnosed with zinc deficiency, along with healing skin lesions and resumption of hair and wool growth.